Results 71 to 80 of about 18,160,584 (274)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
A Comparative Study of the Ideas of Language Philosophers and Shia Usul Scholars on the Ontology of Meaning [PDF]
پژوهشنامه کلام تطبیقی شیعهThe problem of this article is semantics and discussion of the ontology of meaning. In fact, this article deals with the ontological approach in meaning. Existential approach and nonexistent approach.
Mohammad Sadeq Kamelan +2 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Krytyczna analiza propozycji dekryminalizacji przestępstwa zniesławienia
Studia Prawa PublicznegoThere is a noticeable view in the social space about the need to decriminalise the offence of defamation. Such a position is unfounded and is not based on factual and scientific grounds and, in particular, does not take into account the constitutional ...
Marcin Sikora
doaj +1 more source
On Governance, One Concept and Two Contents? [PDF]
دولتپژوهیSome concepts fall victim to their success. Such is the case with the idea of governance in the Islamic Republic of Iran. A vigilant observer notes that this concept is commonly used by politicians and certain elites without any serious consideration ...
Madjid Vahid, Christian Velud
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
From Here to There: Diversity and Interdisciplinary in the Practice of Comparative Literature [PDF]
, 2021 "In the following, I would like to offer a series of preliminary thoughts on the phenomenon of diversity and its possible relations with the discipline of Comparative Literature.
Morris, Paul D.
core