Results 41 to 50 of about 191,243 (258)

Teori Gradasi : Komparasi Antara Ibn Sina, Suhrawardi Dan Mulla Sadra

open access: yesKanz Philosophia: A Journal for Islamic Philosophy and Mysticism, 2015
Prior to Mullā Ṣadrā, the discussion of the gradation (al-tashkīk) was limited on the category of quality and that of quantity, both are known as the differential gradation (al-tashkīk al- tafāḍulī).
Benny Susilo
doaj   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

Rethinking the Good – A Small Taste

open access: yesLaw, Ethics and Philosophy, 2015
This article aims to convey a few of the key claims and arguments of my book, Rethinking the Good: Moral Ideals and the Nature of Practical Reasoning. The article gives an example of a Spectrum Argument, and illustrates that such arguments put pressure ...
Larry Temkin
doaj  

Methodological Aspects of Development of Linguistic and Regional Studies Courses - Evidence from the Arab Studies Course (Arab Countries)

open access: yesOriental Studies, 2018
The paper presents analysis of a new kind of educational courses based on multidisciplinary approach. The course synthesizes the methodologies and advances of regional studies and regional geography, cultural and cross-cultural studies and communication,
A. Stepanova
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Reply to Horta: Spectrum Arguments, the “Unhelpfulness” of Rejecting Transitivity, and Implications for Moral Realism

open access: yesLaw, Ethics and Philosophy, 2015
This article responds to Oscar Horta’s article “In Defense of the Internal Aspects View: Person-Affecting Reasons, Spectrum Arguments and Inconsistent Intuitions”. I begin by noting various points of agreement with Horta.
Larry Temkin
doaj  

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

PHILOSOPHY OF INFORMATION AND TRANSHUMANISM: EXPLICATIONS OF PHILOSOPHICAL ANTHROPOLOGY

open access: yesAntropologìčnì Vimìri Fìlosofsʹkih Doslìdžen', 2019
Purpose. The research is aimed at finding out the grounds, forms and essence of the correlation between the projects of information philosophy and transhumanism from the point of view of the problematics of philosophical anthropology.
O. V. Marchenko, P. V. Kretov
doaj   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Internal or External Grounds for the Nontransitivity of “Better/Worse than”

open access: yesLaw, Ethics and Philosophy, 2015
In his book Rethinking the Good: Moral Ideals and the Nature of Practical Reasoning Larry Temkin contrasts two views of ideals for evaluating outcomes: the Internal Aspects View and the Essentially Comparative View.
Ingmar Persson
doaj  

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