Results 101 to 110 of about 2,138 (256)

Um Estado novo-desenvolvimentista na América Latina? A new developmentalist state in Latin America?

Economia e Sociedade, 2012
A América Latina foi, provavelmente, a região que mais sofreu nos anos neoliberais, porque era inclusive onde as reformas e políticas respectivas foram levadas mais adiante. Por essa razão, foi também a região em que os anos neoliberais primeiro chegaram
Luiz Carlos Bresser-Pereira, Daniela Theuer   +1 more
doaj  

Mutações da cidadania: da comunidade ao estado liberal

Sequência: Estudos Juridicos e Politicos, 2007
Este artigo aborda a evolução do conceitode cidadania, examinando o instituto em seu desenvolvimentohistórico, desde suas origens na culturapolítica clássica até os dias de hoje, quando omesmo é enfocado em seu aspecto formal, a partirdas postulações da teoria do Direito.
Sérgio Cademartori, Daniela Cademartori
openaire   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

O QUE É SOCIALISMO E O QUE É DEMOCRACIA EM NORBERTO BOBBIO

Reflexão
Após a derrocada do socialismo real, N. Bobbio, sem abdicar do ideal socialista, passou a defender os princípios do Estado liberal. O avanço do processo de democratização da sociedade civil (democracia integral) é a condição "sine qua non" da ...
Nayala de S. F. MAIA
doaj  

LIBERALISMO DESENCANTADO

Daimon, 2002
La acción humana tiene consecuencias no intencionales y, frecuentemente, no previsibles. Además, las pretensiones de imponer una concepción del bien chocan con el pluralismo del moral, la idea de que hay opciones morales igualmente válidas pero ...
Enrique Ujaldón
doaj  

THINK-TANKS MADE IN FRANCE: EMPRESARIOS DE UN ESTADO SOCIO-LIBERAL

Espiral estudios sobre Estado y sociedad, 2015
SIN ...
openaire   +3 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Economia, Estado, modernidade - Uma crítica liberal

Revista USP, 1993
Roberto Campos, Oscar Lorenzo Fernandes
openaire   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source