Results 131 to 140 of about 381,897 (302)

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

LIBERALISMO DESENCANTADO

Daimon, 2002
La acción humana tiene consecuencias no intencionales y, frecuentemente, no previsibles. Además, las pretensiones de imponer una concepción del bien chocan con el pluralismo del moral, la idea de que hay opciones morales igualmente válidas pero ...
Enrique Ujaldón
doaj  

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Chronological and Spatial Distribution of Skeletal Muscle Fat Replacement in FHL1‐Related Myopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Variants in the FHL1 gene cause FHL1‐related myopathies (FHL1‐RMs), a group of neuromuscular disorders with diverse clinical presentations. This study aimed to comprehensively characterize the spatial and temporal patterns of skeletal muscle fat replacement throughout the whole body in FHL1‐RMs, to examine disease progression over ...
Rui Shimazaki, Satoru Noguchi, Hotake Takizawa, Yasushi Oya, Yuji Takahashi, Hirofumi Komaki, Hajime Arahata, Shinichiro Hayashi, Ichizo Nishino   +8 more
wiley   +1 more source

Um Estado novo-desenvolvimentista na América Latina? A new developmentalist state in Latin America?

Economia e Sociedade, 2012
A América Latina foi, provavelmente, a região que mais sofreu nos anos neoliberais, porque era inclusive onde as reformas e políticas respectivas foram levadas mais adiante. Por essa razão, foi também a região em que os anos neoliberais primeiro chegaram
Luiz Carlos Bresser-Pereira, Daniela Theuer   +1 more
doaj  

Reformismo Agrario y Liberalismo en Portugal [PDF]

, 2008
Los limitados procesos reformistas agrarios que se desarrollan en Portugal desde la segunda mitad del siglo XVIII hasta la revolución liberal presentan dos sentidos principales: lo primero, en el tiempo del gobierno de Pombal, tiene sobre todo ...
Tengarrinha, José
core   +1 more source

BRASIL: ESTADO INTERVENCIONISTA OU LIBERAL?

REVISTADAACADEMIABRASILEIRADEDIREITOCONSTITUCIONAL, 2019
Átila de Alencar Araripe Magalhães, Renata Albuquerque Lima   +1 more
openaire   +1 more source

Deverá o Estado liberal ser neutro?

, 1997
[Excerto] Introdução Quando se pergunta se o Estado liberal deve ser neutro, de imediato se configuram dois modelos de resposta. O primeiro consiste em dizer que o Estado liberal não deve ser neutro pelo simples facto de que o não poder ser: ought implies can.
openaire   +1 more source

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund, Johan Reutfors, Thomas Frisell, Fredrik Piehl   +3 more
wiley   +1 more source