Results 71 to 80 of about 381,897 (302)

Ideología racial, práctica social y Estado Liberal en Costa Rica

Revista de Historia, 1999
Introducción Hace unos años escuchamos a un amigo describir a una afrolimonense conocida suya de esta manera: “¡Que mujerzota, maje! Tiene el cuerpo de una negra y la cara de una blanca.” Tal comentario, de ninguna manera fuera de contexto en los ...
Lara Elizabeth Putnam
doaj  

La cuestión de la regeneración de la raza en el discurso educativo del laicismo (Ensayos) [PDF]

, 2018
Pese a que el discurso laicista ecuatoriano se inspiró en una utopía educativa de corte integrador e igualitarista, que emergió como la expectativa más importante del triunfo de la revolución liberal de 1895, aparece años más tarde impregnado de ...
Terán Najas, Rosemarie
core  

Estado liberal y Estado totalitario

Revista Ciencias Humanas
La idea marcuseana de que en el seno de la sociedad liberal se va preparando lenta y paulatinamente la concepción totalitaria y, por consiguiente, el estado totalitario sirve de pretexto para unas reflexiones sobre la responsabilidad de dicha sociedad en la complejidad de la guerra. Efectivamente, si de algo decía estar seguro Marcuse había sido que el
openaire   +1 more source

Origens e Desenvolvimento do Ativismo Judicial: Do Estado Liberal ao Estado Social.

Teorias do Direito e Realismo Jurídico, 2016
Este artigo analisará o ativismo judicial respondendo à seguinte indagação: como o papel do Poder Judiciário se modificou com o desenvolvimento dos modelos de Estado? O artigo desenvolverá seu problema analisando a função do Poder Judiciário em cada um destes modelos de Estado de Direito: o Liberal, o Social (em que pese tal Estado não ter sido ...
Alexandre Luna da Cunha, Maria Cristina Zainaghi   +1 more
openaire   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

THOMAS HOBBES: MODERNIDAD E HISTORIA DE LOS CONCEPTOS POLÍTICOS [PDF]

, 2008
Una interpretación liberal del Leviatán. Thomas Hobbes ha sido objeto de muy variadas y contrapuestas interpretaciones1: para algunos, como Leo Strauss, Lacour-Gayet o Harold Laski, el gran publicista del siglo XVII es el campeón del absolutismo en su ...
Rivera García, Antonio
core   +3 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Santo Estado, maldito mercado: de certas esquerdas que são direitas Holy State, damned market: about certain left wings that are right wings

Sociedade e Estado, 2005
É comum na discussão sobre política social e desenvolvimento preservar o Estado e sacrificar o mercado. Historicamente falando, a apreciação positiva do papel do Estado vincula-se ao welfare state, que, mesmo tendo sido fenômeno relativamente curto e ...
Pedro Demo
doaj   +1 more source