Results 241 to 250 of about 6,674,734 (293)

Phytochemical Screening and Protective Effects of <i>Hancornia speciosa</i> Leaf Extract Against Fatty Acid-Induced Lipotoxicity in HepG2 Cells. [PDF]

Molecules
Granato MJMG, Silva FM, Arruda VM, Bezerra AJA, Faria BQ, Carvalho MMF, Teixeira TA, Silva TDC, Prado DG, Souza HOA, Guerra JFDC.   +10 more
europepmc   +1 more source

Matrix Stiffness Orchestrates Mesenchymal Stem Cell Lineage Commitment Toward Osteogenesis and Adipogenesis Through the PIEZO1/SP1/STC2 Axis

Advanced Science, EarlyView.
Matrix stiffness directs mesenchymal stem cell lineage commitment through PIEZO1‐dependent activation of the SP1/STC2 pathway. Stiff matrices favor osteogenesis and suppress adipogenesis, whereas the loss of PIEZO1 function impairs early bone formation. STC2 retains lineage‐regulatory activity even when PIEZO1 is inactive.
Shuo Zhang, Siteng Li, Wenzhong Chen, Qingcheng Song, Haiyue Zhao, Peng Wang, Yiran Zhang, Wenquan Liang, Shaowei Zheng, Juan Wang, Wei Chen, Yanbin Zhu, Yingze Zhang   +12 more
wiley   +1 more source

International Consensus on the Diagnosis and Clinical Management of Idiopathic Short Stature: A Modified Delphi Method.

Horm Res Paediatr
Linglart A, Cianfarani S, Dattani MT, Jorge AAL, Lebenthal Y, Luo X, Maghnie M, Miller BS, Mizuno H, Rapaport R, Collett-Solberg PF, Dauber A.   +11 more
europepmc   +1 more source

Common mental disorders and care provided by the Health Care Network for the rural population: a cross-sectional study, Ceará, Brazil, 2020. [PDF]

Epidemiol Serv Saude
Sombra LL, Campos EM, Pontes RJS, Pessoa VM.   +3 more
europepmc   +1 more source

GSTM4 Suppresses Prostate Cancer Progression by Targeting TRIM27‐mediated ACLY Ubiquitination and Lipid Metabolism

Advanced Science, EarlyView.
GSTM4 enhances the interaction between ACLY and the E3 ubiquitin ligase TRIM27, thereby increasing K48‐linked ubiquitination at the K554 site of ACLY and promoting its degradation. Consequently, GSTM4 regulates lipid synthesis, as well as the proliferation and metastasis of PCa cells, by modulating ACLY stability.
Kang‐Ping Xiong, Fei Liu, Wang Wang, Gang Wang, Kai‐Yu Qian, Sheng Tu, Si‐Ming Chen, Hui‐Min Xu, Shan‐Shan Zhang, Yong Li, Xing‐Huan Wang, Hong Weng   +11 more
wiley   +1 more source

Draft genome of <i>Streptomyces</i> sp. AM6-12, a putative novel species for drug discovery isolated from Brazilian Restinga coastal soil. [PDF]

Microbiol Resour Announc
Oliveira MU, Serafim da Silva VA, Rangel RR, Nhampossa NA, Amaral JRV, Alviano DS, da Conceição CS, Gonçalves CAX, Squizani ED, da Silva S, Macrae A, do Nascimento RP.   +11 more
europepmc   +1 more source

EPI-DRC Brasil: When public health campaigns become scientific evidence - a new paradigm for global nephrology. [PDF]

J Bras Nefrol
Silva Junior GB, Souza E.
europepmc   +1 more source

The Family Health Strategy as a policy of the State: trajectory, institutional capacity and the current primary health care agenda. [PDF]

Cad Saude Publica
Klitzke D.
europepmc   +1 more source

[Temporal trends and clinical-epidemiological profile of visceral leishmaniasis-HIV coinfection in Brazilian states between 2009 and 2024]. [PDF]

Cad Saude Publica
França M, Santos MFDC, Gouveia JG, Antero L.   +3 more
europepmc   +1 more source