Results 151 to 160 of about 3,088,576 (310)

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Entre el Cielo y la Tierra. La Filosofía del Derecho de Jean Bodin y Thomas Hobbes [PDF]

open access: yes, 2005
Jean Bodin y Thomas Hobbes son dos filósofos de la política que preconizaron al Estado absolutista durante el siglo XVI, con ello sentaron los cimientos del moderno Estado europeo.
ESPEJEL MENA, JAIME   +3 more
core  

Estado, sociedade civil e serviço social

open access: yes, 2003
O texto divide-se em duas partes: a.) numa primeira parte tento proceder à fundamentação teórica do Estado Social; b) numa segunda parte procuro demonstrar que a política não se reduz a uma actividade abstracta que se realiza apenas no plano colectivo e desconhece a realidade concreta das comunidades e até dos corpos.
openaire   +3 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Las galerías filtrantes del Alto Lerma: usos y manejos sociales [PDF]

open access: yes, 2011
La ubicación y estudio del manejo social del agua de las galerías filtrantes en el Estado de México no se ha realizado porque se ignora la existencia de este sistema hidráulico.
MONTES HERNANDEZ, ROBERTO   +9 more
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Importance to approve the stamp pro sports & recreation [PDF]

open access: yes, 2016
En este trabajo de grado se pretende realizar una investigación sobre el estado general de la importancia de crear la estampilla pro-deporte dirigida a la infancia, adolescencia y a los Adultos Mayores como población abandonada por parte del Estado ...
Quintero García, Fabian Roberto
core  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Envejecimiento y vulnerabilidad social en el Estado de México, 2010 [PDF]

open access: yes, 2016
Entre las preocupaciones sociales de primer orden está el tema de los grupos etarios de 60 años o más; es decir que en términos demográficos han tenido la fortuna de llegar a la vejez.
GAXIOLA ROBLES LINARES, SERGIO CUAUHTEMOC   +7 more
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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