Results 31 to 40 of about 16,606 (215)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Sobrecarga en el cuidador primario de pacientes con enfermedad en etapa terminal en un hospital del segundo nivel de Hidalgo

open access: yes, 2018
Introduction: The conditions in which the daily activities of the informal caregiver are developed, make it a vulnerable being from the sanitary point of view in this context, the family caregivers become indirectly a victim of the disease due to the ...
Ramírez-Hernández, DL   +10 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Diseño de una política de inventarios multi-escalón multi-productos para una empresa del sector comercio ubicada en el Estado de México [PDF]

open access: yes, 2022
Trabajo Terminal de Grado de MaestríaEl presente trabajo se enfoca al diseño de una política de inventarios ajustada a las necesidades de una empresa del sector comercio ubicada en el Estado de México.
Almazán Munguía, Gael
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Determinación de zonas óptimas para el cultivo de productos agrícolas en el Estado de México, utilizando Evaluación Multicriterio y Sistemas de Información Geográfica [PDF]

open access: yes, 2014
Archivo PDF contiene trabajo terminal de un alumno de la ECATSIGDeterminar las zonas óptimas para el cultivo de productos agrícolas en el Estado de México, mediante el uso de los Sistemas de Información Geográfica (SIG) y Evaluación Multicriterio (EMC ...
Rojas Guadarrama, Arlen
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Modelo para o desenvolvimento de plataforma logística em um terminal : [PDF]

open access: yes, 1999
Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro ...
Duarte, Patrícia Costa
core  

Dolor abdominal agudo en pacientes con enfermedad renal crónica terminal en el servicio de urgencias del HGR n° 17 Cancún.

open access: yes, 2023
En México la enfermedad renal crónica se encuentra entre las 10 primeras causas de mortalidad y representa una de las principales causas de atención en hospitalización y en los servicios de urgencias, se estima que esto vaya en aumento y para el 2025 ...
Sandoval Hernandez, Juan Carlos
core  

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