Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
O Estado e a transformação do espaço urbano: a expansão do Estado nas décadas de 60 e 70 e os impactos no espaço urbano de Florianópolis [PDF]
, 1997 Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências ...
Faccio, Maria da Graça Agostinho
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FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Inconstitucionalidad del artículo 194 apartado a fracción I del código de procedimientos penales del estado de méxico [PDF]
, 2013 El presente trabajo terminal es una investigación con enfoque cualitativa cuyos métodos que se emplearon para dar soporte metodológico son el comparativo hermenéutico, partiendo del objeto de la investigación de la inconstitucionalidad del artículo 194 ...
Quintero Ortiz, Alejandro
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Impacto Urbano del Tren México-Toluca en la Terminal Zinacantepec [PDF]
, 2018 Artículo publicado en modalidad de evaluación de pregaradoEn las siguientes páginas se presenta la el artículo titulado “Impacto urbano del tren MéxicoToluca en la terminal Zinacantepec”, así como la investigación complementaria, como parte de la ...
Hernández López, Sandra Verónica
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FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
PACIENTE EM ESTADO TERMINAL: ASPECTOS RELACIONADOS À (NÃO) CONTINUIDADE DA VIDA
, 2019 O presente artigo aborda a autonomia do responsável legal pela continuidade da vida do paciente em estado terminal. O problema do estudo consiste na análise de qual a capacidade que o responsável legal possui sobre a continuidade da vida em relação à ...
Copatti, Michelli
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Programa de Capacitación en Perspectiva de Género de la Unidad de Igualdad de Género y Erradicación de la Violencia para Personal de Servicio Público de la Secretaría General de Gobierno del Estado de México [PDF]
, 2021 El objetivo general de este Trabajo Terminal de Grado es generar el Programa de Capacitación en Perspectiva de Género de la Unidad de Igualdad de Género y Erradicación de la Violencia para Personal de Servicio Público de la Secretaría General de ...
MIRANDA MACEDO, JAZMIN ANAHI; 591711 +1 more
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