Results 61 to 70 of about 16,606 (215)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Efecto de la musicoterapia en el estado psicológico de los pacientes en estado terminal.

open access: yes, 2012
La música es un factor inherente en la vida del ser humano, acompañándolo en las diferentes fases de su evolución histórica, muchos son los científicos que se han dado a la tarea de determinar el origen del fenómeno musical, enunciándola como un lenguaje
Di Pietrantonio, Adriana
core  

Implicaciones bioéticas en la atención médica a pacientes con cardiopatías en estado terminal [PDF]

open access: yes, 2019
Las enfermedades cardiovasculares representan la principal causa de muerte a nivel mundial y en nuestro país; de ahí que la atención a pacientes con enfermedades cardiovasculares en estado terminal sea común.
Gonzalez-Medina, Kathleen Nicole   +5 more
core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Barcelona Europe South Terminal : Terminal semiautomática de contenedores [PDF]

open access: yes, 2017
Este trabajo intenta profundizar en el mundo del tráfico marítimo de contenedores, dando a conocer el día a día de una terminal puntera y pionera en el mundo como es la Terminal BEST.
Fernández Trillo, Alejandro
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

O licenciamento ambiental como instrumento da politica nacional do meio ambiente [PDF]

open access: yes, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnologico.Análise do Licenciamento Ambiental como instrumento da Política Nacional do Meio Ambiente.
Henning, Elisa.
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Lineamientos arquitectónicos de accesibilidad universal para los CNAMHSV del Estado de México [PDF]

open access: yes, 2023
Trabajo terminal desarrollado en la Especialidad en Accesibilidad ...
Carapia García, Víctor Manuel
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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