Results 71 to 80 of about 4,882,386 (282)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Semiárida, 2020 Se evaluó el comportamiento de los herbicidas Bromoximil; Dcamba + Metsulfurón Metil; Dicamba + MCPA; Terutrina + Triasulfurón y Piclorán + Metsulfurón Metil aplicados en estado de ápices vegetativos; 2,4-D + Dicamba; Bromoximil y Dicamba + MCPA ...
M. Di Plácido, J. Prieto, S. Vázquez
doaj
Dossier commun des revues tic&société et Terminal
, 2016 Avec l’appel à contributions de ce dossier commun « Contrôle social, surveillance et dispositifs numériques » des revues tic&société et Terminal, nous souhaitions revenir sur la question du contrôle social, « que celui-ci soit mis en œuvre par les États,
Vétois, Jacques, Carré, Dominique
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Bondadosa acción medica de humanización de la atención
Revista de la Asociación Colombiana de Dermatología y Cirugía DermatológicaSe presenta el caso de una médica especialista en dolor y cuidado paliativo que, asumiendo el compromiso de humanizar la atención en salud, realiza una acción de gran bondad respondiendo a la solicitud de un paciente en estado terminal.
José María Maya
doaj +1 more source
Revista Brasileira de Terapia Intensiva, 2013 Durante a última década, foi publicado um número significativo de estudos fundamentais que aumentaram o conhecimento atual sobre a sedação em pacientes criticamente enfermos.
Cassia Righy Shinotsuka +1 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Bondadosa acción médica de humanización de la atención. Parte II
Revista de la Asociación Colombiana de Dermatología y Cirugía DermatológicaSe presenta el caso de una médica especialista en dolor y cuidado paliativo que, asumiendo el compromiso de humanizar la atención en salud, realiza una acción de gran bondad respondiendo a la solicitud de un paciente en estado terminal.
José María Maya
doaj +1 more source
Diretivas antecipadas de vontade no Brasil: sua aplicabilidade em psiquiatria [PDF]
Revista BioéticaResumo O objetivo deste estudo foi analisar a percepção de psiquiatras que atuam no Brasil sobre a real aplicabilidade das diretivas antecipadas de vontade em seu trabalho e suas consequências presumíveis, levando em conta que ainda não há uma lei ...
Vania Novelli Domingues +6 more
doaj +6 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source