Results 91 to 100 of about 4,882,386 (282)

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Plan for Development of a Texas Deepwater Terminal

open access: yes, 1974
92 pagesA discussion of environmental effects, socioeconomic effects, site location, engineering, use of facilities, financial aspects, and legal aspects of the project.http://gbic.tamug.edu/request ...
Texas Offshore Terminal Commission
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Avaliação do risco nutricional em pacientes oncológicos graves: revisão sistemática

open access: yesRevista Brasileira de Terapia Intensiva, 2015
RESUMOObjetivo:Revisar sistematicamente os principais métodos para avaliação do risco nutricional utilizados em pacientes oncológicos graves e apresentar aqueles que melhor avaliam os riscos e preveem desfechos clínicos relevantes neste grupo de ...
Ana Valéria Gonçalves Fruchtenicht   +6 more
doaj   +1 more source

Interim Report of the Texas Offshore Terminal Commission

open access: yes, 1973
20 pgs.Much has been written and published and the world has repeatedly been warned by many eminent authorities of an impending energy shortage for the relatively shore term (1985-1990)...
Texas Offshore Terminal Commission
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Nursing professionals' anxiety and feelings in terminal situations in oncology Ansiedades y sentimientos de los profesionales de enfermería en situaciones de terminalidad en oncología Ansiedades e sentimentos de profissionais da enfermagem nas situações de terminalidade em oncologia

open access: yesRevista Latino-Americana de Enfermagem, 2007
This study aimed to investigate, through a cross-sectional study, factors that influence anxiety levels and feelings of a nursing team who care for terminal patients with cancer.
Daniella Antunes Pousa Faria   +1 more
doaj   +1 more source

Cuidado humanizado de enfermería al paciente con enfermedad oncológica en estado terminal

open access: yes, 2023
El cáncer es considerado una de las principales causas de morbilidad y mortalidad en el mundo, cuyo diagnóstico supone para las personas una situación difícil de afrontar, no sólo por los cambios físicos que desarrollan, sino también por las alteraciones psicológicas que acarrea. Objetivo: Determinar la percepción del paciente con enfermedad oncológica
openaire   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy