Results 101 to 110 of about 4,882,386 (282)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
ANÁLISE DO FILME “O TERMINAL”: por que um Estado é importante para um indivíduo? [PDF]
Este artigo propõe-se a analisar o filme “O Terminal”, dirigido por Steven Spielberg e estrelado por Tom Hanks, relacionando-o com aspectos do campo jurídico, em especial, a Teoria Geral do Estado.
Beatriz Fonseca Cruz
core +1 more source
Critical health-disease transition in the family: Nursing intervention in the lived experience
Revista Brasileira de EnfermagemObjective: To analyse the strategies found by families to deal with the situation of critical illness, in their lived experience in a family and in an inpatient context.
Anabela Pereira Mendes
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Wilmington Marine Terminal, scrapbook of photographs, 1942-1945
, 1942 Terminal worker loading cargo into a railroad car using a ...
Wilmington Marine Terminal
core +2 more sources
Doença crítica crônica: estamos salvando ou criando vítimas?
Revista Brasileira de Terapia IntensivaRESUMO Os avanços tecnológicos que permitem dar suporte às disfunções de órgãos levaram a um aumento nas taxas de sobrevivência para a maioria dos pacientes críticos. Alguns destes pacientes sobrevivem à condição crítica inicial, porém continuam a sofrer
Sergio Henrique Loss +5 more
doaj +1 more source
Terminal City Dispatches [PDF]
, 1998 Photocopy of a Terminal City Magazine review for a Satina Saturnina performance at The Brickyard.
core
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Asistencia integral en cuidados paliativos de pacientes en estado terminal en Colombia
, 2014 Este trabajo de investigación resume los parámetros generales bajo los cuales se presta el servicio de salud en Colombia. Muestra de manera somera los diferentes cambios que el Sistema de Salud en Colombia ha experimentado durante los últimos 60 años y confronta la actualidad de lo que se plantea en dicho Sistema contra la realidad que afrontan muchos ...
Valencia Escobar, Edgar Adrián +1 more
openaire +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source