Results 111 to 120 of about 270,351 (261)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Revista do Colégio Brasileiro de CirurgiõesOBJETIVO: Estudar os efeitos da isquemia e reperfusão hepática total sobre acúmulo de neutrófilos no íleo terminal e cólon sigmóide de ratos, em condições de normalidade e submetidos ao estado de choque hemorrágico controlado.
Mauro José Fontelles, Mario Mantovani
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Le comportement des cocotiers hybrides à l'égard du leaf blight dû à B. theobromae Pat. Observations au champ [PDF]
, 1991 Le leaf blight du cocotier, dû au champignon Botryodiplodia theobromae Pat., provoque actuellement la chute des rendements du cocotier dans l'état de Sergipe au Brésil et, plus récemment, il a occasionné des dégâts importants dans les plantations ...
Bezerra, A.P.O. +2 more
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Spawning of yellowfin tuna and skipjack in the Eastern Tropical Pacific, as inferred from studies of gonad development [PDF]
, 1961 (PDF contains 70 pages.
Orange, Craig J.
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Desarrollo floral en cereales de invierno en distintas épocas de siembra
Semiárida, 2020 En trigo pan, trigo candeal y cebada cervecera, el ápice en estado de doble lomo y de espiguilla terminal diferenciada, marca el límite para realizar distintas prácticas agronómicas. El objetivo del presente trabajo fue estudiar el desarrollo del ápice y
C. A. Campanari
doaj
1.5V fully programmable CMOS Membership Function Generator Circuit with proportional DC-voltage control [PDF]
, 2013 A Membership Function Generator Circuit (MFGC) with bias supply of 1.5 Volts and independent DC-voltage programmable functionalities is presented. The realization is based on a programmable differential current mirror and three compact voltage-to-current
Molinar-Solis, J. E. +4 more
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source