Results 111 to 120 of about 678,509 (260)

La construcción de la imagen de México en Estados Unidos desde una perspectiva de riesgo

open access: yesFrontera Norte, 2008
En este artículo se analiza la manera en que se ha construido la imagen de México en Estados Unidos a partir de una idea de riesgo, y el papel que ha tenido la frontera en este proceso.
Mario Alberto Velázquez García
doaj  

Formal and real fiscal federalism in Argentina [PDF]

open access: yes, 2003
In this note we describe, on the one hand, the formal institutional structure of the Argentine fiscal federalism. Then, on the other hand, we show how fiscal federalism really works in Argentina.
Besfamille , Martin, Sanguinetti, Pablo
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Los estados desarrollistas en el este asiático: aportaciones institucionales y límites históricos

open access: yesRevista Iberoamericana de Estudios de Desarrollo, 2014
Developmental State conceptualization emerged during second half of the XX century as an explanative hypothesis for the fast growing economies in the Asian northeast.
Fernando DE LA CRUZ PREGO
doaj  

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Relaciones entre indocumentados y “coyotes”

open access: yesEstudios Fronterizos, 1983
Este ensayo nació de la experiencia adquirida en el trabajo de campo, la intención es sistematizar, dentro de lo posible y de acuerdo con la información limitada, las observaciones logradas durante las pláticas sostenidas con cientos de indocumentados ...
Carlos H. Zazueta
doaj  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

América Latina y El Caribe: Dictaduras militares y democracia

open access: yesLa Universidad, 2018
Uno de los temas más polémicos, desde todo punto de vista, en las relaciones entre Estados Unidos y los países de América Latina es el referido a la democracia, no sólo por las múltiples interpretaciones de que ha sido objeto, sino por los límites ...
Carlos Oliva
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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