Results 131 to 140 of about 696,648 (255)

Promesas y límites del policy analysis en Estados Unidos

open access: yesDocumentación Administrativa, 1990
Carles Boix
doaj   +1 more source

Los latinos, los migrantes y la descolonización del Imperio estadounidense en el siglo XXI

open access: yesTabula Rasa: Revista de Humanidades, 2008
Este artículo analiza las marchas multitudinarias de inmigrantes en los Estados Unidos durante los meses de marzo, abril y mayo de 2006 en los Estados Unidos.
RAMÓN GROSFOGUEL   +1 more
doaj  

Estados Financieros 30 de junio de 1974

open access: yes, 1974
46 páginasEl presente documento presenta los resultados tras haber examinado los estados financieros del IICA del año al 30 de junio de 1974. Dicha revisión se practicó de acuerdo con las normas de auditoría usualmente aplicadas e incluyó pruebas ...
Instituto Interamericano de Cooperación para la Agricultura (IICA)   +2 more
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

América Latina y El Caribe: Dictaduras militares y democracia

open access: yesLa Universidad, 2018
Uno de los temas más polémicos, desde todo punto de vista, en las relaciones entre Estados Unidos y los países de América Latina es el referido a la democracia, no sólo por las múltiples interpretaciones de que ha sido objeto, sino por los límites ...
Carlos Oliva
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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