Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
[Are foods of the Brazilian "staple food basket" safe for consumption?] [PDF]
Ripke MO, Corralo VDS, Lutinski JA.
europepmc +1 more source
[Regulation of pesticide residues in food in the MERCOSUR: a much needed discussion for health surveillanceRegulación de los residuos de productos agrotóxicos en los alimentos en el MERCOSUR: una discusión necesaria para la vigilancia de la salud]. [PDF]
Centurión MPB +3 more
europepmc +1 more source
Boston Brass, quinteto de cobres (Estados Unidos)
Concierto interpretado por Boston Brass. Del vasto universo musical de los quintetos de bronces, es quizás el Bastan Brass uno de los más llamativos, sobresalientes, y en quien resalta una larga historia de grabaciones clásicas, presentaciones memorables
Boston Brass - Quinteto de cobres (Estados Unidos)
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Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Challenges faced by Latin America health systems. [PDF]
Castro L.
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
[Populational choreography: historical cartography, politics and environment in the dispute between Piauí and Ceará surrounding the Ibiapaba mountain]. [PDF]
Sousa LCAD.
europepmc +1 more source
Cuarteto americano, cuarteto de cuerdas (Estados Unidos) y Menahem Pressler, iano (Estados Unidos)
Concierto interpretado por Menahem Pressler y Cuarteto Americano. Menahem Pressler es miembro fundador y pianista del Trío Beaux Arts. Con una carrera que se extiende por más de cinco décadas, es reconocido como uno de los músicos más distinguidos del ...
Cuarteto americano - Cuarteto de cuerdas (Estados Unidos); Pressler, Menahem - Piano (Estados Unidos)
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Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source

