Results 271 to 280 of about 192,226 (349)

Correlating Laryngoscopic and Clinical Findings With Airway Intervention in Angioedema

open access: yesLaryngoscope Investigative Otolaryngology, Volume 11, Issue 6, December 2026.
ABSTRACT Objective(s) To evaluate whether specific presenting symptoms and laryngoscopic subsite involvement in aerodigestive angioedema predict clinical severity, defined by airway intervention, hospital admission, and length of stay (LOS). A secondary objective was to assess the performance of a reduced symptom‐based model for predicting intubation ...
Noah Thornton   +7 more
wiley   +1 more source

Synergistic Regulation of Biomaterials and Macrophages: A Novel Paradigm in Immunotherapy

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 4, December 2026.
Bioengineered materials mediating the modulation of macrophage plasticity and inflammatory signals in the tumor microenvironment effectively remodel immunoregulatory states, boost antitumor immunity, and promote tissue repair, achieving synergistic therapeutic outcomes.
Jiayu Zhang   +16 more
wiley   +1 more source

A designer protein binder of KRAS enables exogenous protein degradation

open access: yesProtein Science, Volume 35, Issue 12, December 2026.
Abstract Targeted protein degradation has emerged as a powerful strategy for modulating intracellular proteins, particularly those lacking traditional small‐molecule binding pockets. While protein‐based degraders expand this approach to undruggable targets, they typically require intracellular expression in target cells, limiting their utility as ...
Aniekan Okon   +5 more
wiley   +1 more source

Evaluation of Carotenoid Bioaccessibility in Selected Dietary Sources Using a Modified INFOGEST <i>In Vitro</i> Digestion Protocol. [PDF]

open access: yesACS Food Sci Technol
Rodríguez-Rodríguez E   +3 more
europepmc   +1 more source

Deep learning‐based structure modeling of the Treponema pallidum proteome: Insights into pathogenesis and syphilis vaccine development

open access: yesProtein Science, Volume 35, Issue 12, December 2026.
Abstract Treponema pallidum ssp. pallidum, the causative agent of syphilis, has a small proteome and encompasses numerous strains. Knowledge gaps remain in understanding the molecular mechanisms of pathogenesis of this bacterium, as well as the structure and function of the full complement of proteins encoded by T. pallidum.
Simon Houston   +5 more
wiley   +1 more source

From Prototype to Sustainable Food Production: Translational Barriers and Design Priorities for Agricultural Biosensing Systems

open access: yesJournal of Sustainable Agriculture and Environment, Volume 5, Issue 4, December 2026.
ABSTRACT Agricultural biosensors could advance sustainable food production by enabling timely detection of crop stress, pathogens, nutrient imbalances, and environmental contaminants. Despite decades of research, however, robust commercial biosensing platforms remain uncommon because analytical performance under controlled conditions does not ...
Frank Efe Erukainure   +4 more
wiley   +1 more source

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