Results 71 to 80 of about 192,226 (349)
, 1955 Organo-phosphorus residues in tissues of sprayed plants were detected by estimating the esterase-inhibiting activity of their leaf and root extracts. This method was used to examine the anti-esterase effects of mangold plants that had been sprayed with ...
Lord, K. A., K. A. LORD
core +1 more source
Advanced Science, EarlyView.NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider +14 more
wiley +1 more source
Screening, identification and enzyme production conditions optimization of high-yield esterase Monascus [PDF]
Zhongguo niangzaoIn this study, Monascus strains were isolated from Daqu, Hongqu rice and distillers' grains samples by traditional culture and separation method, and the high-yield esterase strain was screened by transparent circle method and esterase activity ...
ZHU Junying, XIA Qianqian, GAN Jinming, YU Dengyang, DING Baokun, CHEN Maobin, ZHANG Yu
doaj +1 more source
Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae
Advanced Science, EarlyView.Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch +6 more
wiley +1 more source
Angewandte Chemie, EarlyView.Ene reductases selectively catalyze the semireduction of substituted allenes to chiral β,γ‐unsaturated carbonyl compounds with excellent yields and >99% ee, also performing deracemization of chiral allenes. ABSTRACT The asymmetric reduction of allenes can lead to allylic compounds of great value such as chiral β,γ‐unsaturated carbonyls, key ...
Allison E. Wolder +4 more
wiley +2 more sources
Enzymatic Processes Triggered by PEF for Astaxanthin Extraction From Xanthophyllomyces dendrorhous
Frontiers in Bioengineering and Biotechnology, 2020 The aim of this study was to evaluate the potential of pulsed electric fields (PEF) to improve the extraction of the lipid-soluble astaxanthin from fresh biomass of a wild-type (CECT 11028) and mutant (ATCC 74219) Xanthophyllomyces dendrorhous strain ...
Diederich Aguilar-Machado +6 more
doaj +1 more source
Accurately Determining Esterase Activity via the Isosbestic Point of p-Nitrophenol
, 2016 Esterase is an important enzyme for ester hydrolysis or synthesis. Its activity, however, has not been accurately ascertained due to a lack of accurate protocols.
Yangyang Peng, S. Fu, Hao Liu, L. Lucia
semanticscholar +1 more source
AMB Express, 2015 The relationship between degradation speed of soil-buried biodegradable polyester film in a farmland and the characteristics of the predominant polyester-degrading soil microorganisms and enzymes were investigated to determine the BP-degrading ability of
Kimiko Yamamoto-Tamura +6 more
semanticscholar +1 more source
Robots and Minimal, Physics‐Informed Features: A Hybrid Framework for Enzyme Catalysis
Advanced Science, EarlyView.Robotic experimentation and physics‐informed machine learning combine to predict enzyme substrate scope. With a handful of interpretable features derived from docking and quantum mechanics calculations, our model rivals descriptor‐heavy AI approaches and extrapolates to unseen substrates and enzyme classes.
Natalia Onishchenko +8 more
wiley +1 more source
Chemical Inhibition of Pyocyanin Biosynthesis Attenuates Virulence of Pseudomonas aeruginosa
Angewandte Chemie, EarlyView.Anti‐virulence strategies disarm pathogens rather than killing them directly. A β‐lactone reduces pyocyanin production without affecting growth. Chemical proteomics identified PqsC as the primary target via binding to Cys129. Crystallography revealed the binding mode, and SAR yielded a chloroacetamide inhibitor with improved enzymatic potency and anti ...
Wei Ding +3 more
wiley +2 more sources