Results 81 to 90 of about 192,226 (349)

Arabidopsis SFAR4 is a novel GDSL-type esterase involved in fatty acid degradation and glucose tolerance

Botanical Studies, 2015
SFARs (seed fatty acid reducers) belonging to the GDSL lipases/esterases family have been reported to reduce fatty acid storage and composition in mature Arabidopsis seeds.
Li-Min Huang, C. Lai, L. Chen, M. Chan, J. Shaw   +4 more
semanticscholar   +1 more source

AHR‐Responsive Carbon Dots Orchestrate Skin Wound Healing and Colonic Mucosal Repair via Treg‐Mediated Macrophage Efferocytosis

Advanced Science, EarlyView.
Guided by pharmacophore modeling and molecular docking, aryl hydrocarbon receptor (AHR)‐responsive carbon dots were synthesized. They bind directly to AHR and expand gut‐resident regulatory T (Treg) cells. Treg‐derived C‐C motif chemokine ligand 1 (CCL1) enhances macrophage efferocytosis, creating a pro‐regenetative niche that promotes colonic mucosal ...
Zilu Zhu, Han Zhang, Shuai Lin, Wenqian Zheng, Xin Li, Xiaowei Xu, Ruili Yang   +6 more
wiley   +1 more source

Downsizing Electrophilic MAX‐Derived Helical Zipper Peptides to Covalently Bind and Degrade Oncogenic MYC

Angewandte Chemie, EarlyView.
Oncogenic MYC is a transcription factor that is difficult to inhibit. However, precise positioning of an acrylamide electrophile in MAX to covalently bond to the unique Cys438 in MYC, enabled shortening and optimizing of MAX‐derived, helix‐constrained peptides with high‐affinity and selectivity.
Aline Dantas de Araujo, Lei Luo, Mahan Azad, Miao Yu, Jody M. Mason, Junxian Lim, Timothy A. Hill, David P. Fairlie   +7 more
wiley   +2 more sources

Determination of the Insecticide Resistance Mechanisms Using Biochemical Methods in the Aphis gossypii Glover (Hemiptera: Aphididae) Populations Damaging on Cotton in Turkey

Journal of Agricultural Sciences, 2008
This research was performed between 2000 and 2003, to explore the role of the mechanisms in conferring insecticide resistance of Aphis gossypii populations collected from the cotton areas of the Mediterranean region of Turkey using biochemical methods ...
Graham D. Moores, M.oktay Gürkan, A. Sibel Velioğlu, Cem Erdoğan   +3 more
doaj  

Esterase profile in the postembryonic development of Rhipicephalusmicroplus Perfil esterásico durante o desenvolvimento pós-embrionário de Rhipicephalusmicroplus

Pesquisa Agropecuária Brasileira, 2007
The objective of this work was to analyze the pattern of esterase activity in the development stages of Rhipicephalus microplus by nondenaturing polyacrylamide gel electrophoresis using specific staining for esterase.
Milla Alves Baffi, Cícero Donizete Pereira, Guilherme Rocha Lino de Souza, Carlos Roberto Ceron, Ana Maria Bonetti   +4 more
doaj   +1 more source

Characterization of carboxylesterases involved in the insecticide resistance of Culex quinquefasciatus from the Caribbean and South America. [PDF]

The organophosphate resistance-associated elevated esterases Estα2, Estβ1 and Estβ2 were purified to homogeneity from larvae of the Cuban Habana strain.
Small, Graham John
core   +1 more source

Dual‐Target Nectin‐4/FAP Heterobivalent Probe 68Ga/177Lu‐FZ‐NF‐1 for Triple‐Negative Breast Cancer: Preclinical Theranostic Evaluation and First‐in‐Human Translation

Advanced Science, EarlyView.
A novel hetero‐bivalent agent, 68Ga/177Lu‐FZ‐NF‐1, concurrently targets Nectin‐4 and FAP in triple‐negative breast cancer. It yields significant preclinical tumor regression and clinically identifies additional metastatic lesions missed by 18F‐FDG PET, demonstrating promising theranostic potential for personalized management.
Ye Li, Li Sun, Xiaoyu Pan, Shuyi Lin, Dongliang Wang, Jianping Zhang, Fengshuang Qiu, Bin Zhu, Lingzhou Zhao, Fengsheng Zhang, Liyan Bai, Bingxin Gu, Xiaoping Xu, Shaoli Song   +13 more
wiley   +1 more source

Inhibition of acetylcholine esterase and butyrylcholine esterase with isoquinoline alkaloids

, 1985
The inhibition of the mentioned enzymes with 16 natural and modified isoquinoline alkaloids was investigated. Protoberberines are very strong inhibitors of both enzymes, quaternary tetrahydroprotoberberines and benzylisoquinolines are comparably strong ...
Jaromír Stejskal, Jan Kovář, Jiří Slavík   +2 more
core   +1 more source

Critical Roles of O‐Acetylation Revealed by Synthetic Trisaccharide Antigens for a Broad‐Spectrum Anti‐Salmonella Vaccine

Advanced Science, EarlyView.
A synthetic glycoconjugate vaccine based on a diacetylated Salmonella trisaccharide elicits broadly protective antibodies against four major human pathogenic serovars. Mechanistic studies identify 2,3‐di‐O‐acetylation of rhamnose as a critical determinant of antigen recognition and breadth of protection, establishing a new strategy for broad‐spectrum ...
Xingling Pan, Soham Maity, Herbert Kavunja, Yuvarani Murali, Ting‐An Chen, Chang‐xin Huo, Scott M. Baliban, Xuefei Huang   +7 more
wiley   +1 more source

Optimization of solid-state fermentation conditions for feruloyl esterase production by Aspergillus awamori [PDF]

Zhongguo niangzao
Using feruloyl esterase activity as the response value,the conditions for producing feruloyl esterase by Aspergillus awamori were optimized through single factor tests and response surface experiments.The results showed that the optimal fermentation ...
ZHANG Ting, LIU Xiying, CHEN Tao
doaj   +1 more source