Results 101 to 110 of about 124,633 (302)

Resistance of Aedes aegypti from the state of São Paulo, Brazil, to organophosphates insecticides

open access: yesMemorias do Instituto Oswaldo Cruz, 2003
Since the reintroduction of Aedes aegypti in the state of São Paulo, in the middle of the 1980-decade, organophosphate insecticides are being used to control the dengue vector. In 1996, an annual program for monitoring the susceptibility of Ae.
Maria de Lourdes G Macoris   +5 more
doaj   +1 more source

Use of pyrethroid analogues to identify key structural features for enhanced esterase resistance in Helicoverpa armigera (Hubner) (Lepidoptera: Noctuidae)

open access: yes, 2007
It has been reported previously that the major resistance mechanism to pyrethroid insecticides by the cotton bollworm Helicoverpa armigera (Hubner) in Australia is a consequence of overproduction of esterase isoenzymes.
Gunning, R. V.   +11 more
core   +1 more source

THSD7A Exacerbates Atherosclerosis via Activation of Signaling Axis αvβ3/CEBPD/IL1A

open access: yesAdvanced Science, EarlyView.
THSD7A exerts pro‐inflammatory effects and exacerbates atherosclerosis. Mechanistically, THSD7A regulates endothelial cell inflammation and atherosclerosis by activating the αvβ3/CEBPD/IL1A signaling axis. THSD7A is not only a genetic marker but also a potential therapeutic target for coronary artery disease (CAD).
Jiankun Liu   +15 more
wiley   +1 more source

Generalizable Strategies for the Synthesis of Cereblon‐Recruiting PROTAC Prodrugs

open access: yesAngewandte Chemie, EarlyView.
Cereblon‐recruiting PROTACs remain challenging to derivatize for prodrug‐based delivery. In this study, three complementary conjugation strategies enabled the efficient synthesis of cleavable PROTAC prodrugs with tunable release kinetics that can be incorporated into a library of PEGylated constructs and bottlebrush prodrugs.
Aiden X. Wang   +7 more
wiley   +2 more sources

The effect of Nozevit on leucine aminopeptidase and esterase activity in the midgut of honey bees (Apis mellifera)

open access: yesVeterinární Medicína, 2013
The histochemical activity of aminopeptidase and non-specific esterase, both important enzymes of intermediate metabolism in the mid gut of honeybees (Apis mellifera), was investigated.
I. Tlak Gajger, S. Nejedli, Z. Kozaric
doaj   +1 more source

Chromosomal location of the amplified esterase genes conferring resistance to insecticides in Myzus persicae (Homoptera: Aphididae)

open access: yes, 1995
A genomic probe encompassing most of an esterase gene (E4) that is amplified in insecticide-resistant Myzus persicae was hybridized in situ to mitotic and meiotic chromosome preparations of aphid clones of known esterase type and resistance level ...
Field, L. M.   +7 more
core   +1 more source

Oral Nanomicelle‐Mediated Sequential Butyrate Production in the Intestine for Ulcerative Colitis and Immunosuppression Treatment

open access: yesAdvanced Science, EarlyView.
After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin   +9 more
wiley   +1 more source

Lysozymes' esterase activity

open access: yesFEBS Letters, 1983
A non‐specific esterase activity of hen lysozyme (c‐type) has previously been described: histidine was claimed to be involved in this activity. The present letter reports that a histidine‐less lysozyme from the duck egg‐white (c‐type) as well as a goose lysozyme (g‐type) possess such an esterase activity determined using p‐nitrophenylacetate.
Jollès, Jacqueline, Jollès, Pierre
openaire   +2 more sources

A carboxylesterase, Esterase-6, modulates sensory physiological and behavioral response dynamics to pheromone in Drosophila [PDF]

open access: yes, 2012
Conclusions: Our study presents evidence that Est-6 plays a role in the physiological and behavioral dynamics of sex pheromone response in Drosophila males and supports a role of Est-6 as an odorant-degrading enzyme (ODE) in male antennae.
Francois, Adrien   +6 more
core  

Hereditary angioedema (HAE) in children and adolescents : a consensus on therapeutic strategies [PDF]

open access: yes, 2012
Hereditary angioedema due to C1 inhibitor (C1 esterase inhibitor) deficiency (types I and II HAE-C1-INH) is a rare disease that usually presents during childhood or adolescence with intermittent episodes of potentially life-threatening angioedema ...
Martinez-Saguer, I   +35 more
core   +2 more sources

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