This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao +8 more
wiley +1 more source
SFGP 2007 - Investigation of a Novel Principle of Chemical Grafting for Modification of Cellulose Fibers [PDF]
Natural cellulose fibres have been employed for packaging applications for a long time. Their use, however, has been hampered by their high hydrophilicity and their moisture sensitivity.
Berlioz, Sophie +3 more
core +1 more source
This study develops a 3D co‐culture and co‐differentiation system for porcine muscle stem cells (pMuSCs) and mesenchymal stem cells (pMSCs) on edible starch‐based scaffolds. The system simultaneously generates myotubes and adipocytes without using serum or chemical inducers.
Xin Guan +9 more
wiley +1 more source
Unexpected Accumulation of ncm\u3csup\u3e5\u3c/sup\u3eU and ncm\u3csup\u3e5\u3c/sup\u3es\u3csup\u3e2\u3c/sup\u3eU in a \u3cem\u3etrm9\u3c/em\u3e Mutant Suggests an Additional Step in the Synthesis of mcm\u3csup\u3e5\u3c/sup\u3eU and mcm\u3csup\u3e5\u3c/sup\u3es\u3csup\u3e2\u3c/sup\u3eU [PDF]
Background Transfer RNAs are synthesized as a primary transcript that is processed to produce a mature tRNA. As part of the maturation process, a subset of the nucleosides are modified.
Anderson, James T. +3 more
core +1 more source
Cross‐linked polysaccharide binders derived from potato starch and xanthan gum enable fully water processed EDLC electrodes with improved mechanical integrity and long‐term electrochemical stability at high voltage. ABSTRACT Advancing sustainable energy storage technologies has increased the focus on water processable binders for high‐performance ...
Mahdi Karimi Jafari +3 more
wiley +1 more source
Application of response surface methodology to optimize the treatment process of high conversion of free fatty acids using (1R)-(-)-camphor-10-sulfonic acid and iron(III) sulphate [PDF]
This study investigates biodiesel production from acidic crude palm oil using one homogeneous catalyst, (1R)-(-)-camphor-10-sulfonic acid (10-CSA), and one heterogeneous catalyst, iron(III) sulphate, focusing on their catalytic activity, recyclability ...
Hayyan Adeeb +9 more
doaj +1 more source
Catechol Derivative‐Based Bioadhesives: Molecular Design for Precision Medical Adhesion
This study utilizes tree‐inspired side‐chain engineering to graft five catechol derivatives onto PVA, systematically revealing how side‐chain length and substituents regulate adhesion and cohesion properties. Among them, the PVA‐CA patch demonstrates superior tissue adhesion, biocompatibility, and promotes regeneration, establishing a programmable ...
Xueyu Wang +8 more
wiley +1 more source
Blends of Nitrile Butadiene Rubber/poly (Vinyl Chloride): the Use of Maleated Anhydride Castor Oil Based Plasticizer [PDF]
Recently, much attention has been focused on research to replace petroleum-based plasticizers, with biodegradable materials, such as biopolymer which offers competitive mechanical properties.
Dewi, I. R. (Indiah) +2 more
core
Anaerobic co-digestion of residues from the cold pressing and trans-esterification of oilseed rape (OSR) with other farm wastes was considered as a means of enhancing the sustainability of on-farm biodiesel production.
Banks, Charles J. +2 more
core +1 more source
By grafting dense long double‐brush chains, we synthesized bottlebrush networks with high theoretical enthalpy. Their low entanglement, combined with dynamic bonds, promotes crystalline domain reorganization and minimizes enthalpy loss, achieving a record enthalpy of 240.7 J·g−1.
Qiguang Liu +7 more
wiley +1 more source

