Results 211 to 220 of about 140,535 (311)

The photoswitchable ABAMIs for the future regulation of GWT1 in a spatiotemporal level

open access: yesSmart Molecules, EarlyView.
The GWT1‐targeted azobenzene‐aminopyridine derivatives (ABAMIs), sensitive to the light at wavelengths from 365 to 520 nm, are separately developed as photochromic ligands to regulate bioactivity as well as the GWT1 functions. These molecules are smart tools in photopharmacological studies, giving an innovative method for understanding functional GWT1 ...
Qian Ding   +8 more
wiley   +1 more source

Redox‐responsive dual‐drug nanomedicine integrating cisplatin and trypsin for synergistic reversal of tumor chemoresistance

open access: yesSmart Molecules, EarlyView.
This study presents a novel glutathione‐activatable prodrug nanomedicine (cRGD‐PEG‐PGlu‐NP (ssTrypsin & CDDP)) that co‐encapsulates cisplatin and a masked protease to combat cisplatin resistance. The dual‐drug system selectively targets resistant tumor cells, enhancing the efficacy of cisplatin while minimizing systemic toxicity.
Xiaolan Yin   +10 more
wiley   +1 more source

Dimethyl‐, Diethyl‐, and Propylene Carbonates: An Emerging Class of Green Solvents for Organic Synthesis

open access: yesThe Chemical Record, EarlyView.
This review highlights recent advances in the use of organic carbonates, dimethyl carbonate (DMC), diethyl carbonate (DEC), and propylene carbonate (PC), as solvents in organic synthesis. Based on over seventy studies from the past 6 years, it shows their application in different organic reaction types, emphasizing their role in safer and more ...
Gabriela T. Quadros   +5 more
wiley   +1 more source

Amine-to-Halogen Exchange Enables an Amine-Acid Etherification. [PDF]

open access: yesJACS Au
McGrath A   +11 more
europepmc   +1 more source

Metal‐Free Electrophilic Borylative Cyclizations of Alkynes

open access: yesThe Chemical Record, EarlyView.
Metal‐free borylative cyclizations based on electrophilic alkyne activation by boron Lewis acids provide efficient access to borylated hetero‐ and carbocycles. Early studies using B(C6F5)3 displayed limited scope and application, whereas recent ClBcat‐ and BCl3‐based methods enable mild CB and CC/CX bond formation for the synthesis of cycles ...
Jaime Mateos‐Gil   +3 more
wiley   +1 more source

A Bottom-Up Synthetic Approach to Polyethylene Furanoate Model Compounds. [PDF]

open access: yesJ Org Chem
Mondal K   +5 more
europepmc   +1 more source

Advances in cholesterol and lipoproteins detection for healthcare: A review

open access: yesVIEW, EarlyView.
Cholesterol is one of the main biomarkers related to the development of cardiovascular diseases. Its detection still relies on traditional methods of analysis, such as gas and liquid chromatographies. Detection of free cholesterol in saliva with redox or enzymatic sensors or detection of lipoproteins in blood with aptamer sensors are currently the most
Jacopo Giaretta   +7 more
wiley   +1 more source

Mechanism-Guided Precision Hydrolysis of Early Transition Metals to Access (Mixed-Metal) Oxo Clusters. [PDF]

open access: yesAngew Chem Int Ed Engl
Parammal MJ   +5 more
europepmc   +1 more source

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