Results 231 to 240 of about 139,266 (240)

Songorine inhibits mitophagy in chronic heart failure via the TBC1D15/Fis1/Rab7A pathway

British Journal of Pharmacology, EarlyView.
Abstract Background and purpose Songorine (SGR) is an alkaloid extracted from Aconitum carichaelii Debx. and has a demonstrated role in cardiac dysfunction. Chronic heart failure (CHF) is a severe clinical syndrome leading to functional impairment and death, primarily due to the deterioration of energy metabolism in cardiomyocytes. However, the precise
Wenxiu Liu, Xingju Zou, Yang Zheng, Chen Sun, Cheng Peng   +4 more
wiley   +1 more source

Adding Yttrium to SO₄ ^2-/ZrO₂ Catalysts To Improve the Synthesis Performance of Esters for Electrical Insulating Oils. [PDF]

ACS Omega
Kwak BS, Kim E, Jun T, Kim AR, Moon Y, Lee J, Kang M, Park H.   +7 more
europepmc   +1 more source

Second‐generation prokineticin PKR1 receptor agonists: Advancing cardioprotection against chemotherapy‐induced toxicity

British Journal of Pharmacology, EarlyView.
IS39, a novel non‐peptide PKR1 agonist, confers cardioprotection against doxorubicin‐induced toxicity. IS39 activates PKR1‐mediated pro‐survival signalling in cardiomyocytes, reducing reactive oxygen species (ROS), DNA damage and fibrosis markers. In vivo, IS39 preserves cardiac geometry and function in mice exposed to chronic doxorubicin challenge ...
Anais Audebrand, Simone Brogi, Mustafa Tezeren, Andrea Tafi, Omer H. Ocak, Hasan Koyuncu, Igor Tetko, Laurent Désaubry, Canan G. Nebigil   +8 more
wiley   +1 more source

Novel Bioactive Multifunctional Polyphenols: A Chemo-Enzymatic Approach. [PDF]

Chemistry
Flourat AL, Thiébault E, Martinez A, Brunissen F, Dosso A, Oszust F, Blaise S, Romier B, Allais F.   +8 more
europepmc   +1 more source

Diarrhetic Shellfish Poisoning Toxins: Current Insights into Toxicity, Mechanisms, and Ecological Impacts. [PDF]

Mar Drugs
Bouda H, El Bourki R, Fattah A, Takati N.   +3 more
europepmc   +1 more source

Engineering Functional PVA: A Comprehensive Review of Chemical Modifications and Prospective Developments. [PDF]

ACS Polym Au
Vu NQ, Le TM, Ngo ANB, Nguyen MHT, Liao YC, Tran TT.   +5 more
europepmc   +1 more source

Mechanical Ball Milling-Assisted Synthesis of Esterified Starch for Polybutylene Succinate Blend with Improved Performance. [PDF]

Molecules
Cai W, Huo C, Tan J, Chen Z, Yin Y, Jin Y.   +5 more
europepmc   +1 more source

Design and Optimization of Pullulan-Isononanoate Films with Bioactive-Loaded Liposomes for Potential Biomedical Use. [PDF]

Polymers (Basel)
Karkad AA, Marinković A, Jovanović A, Simić K, Ivanović S, Milošević M, Erceg T.   +6 more
europepmc   +1 more source