Results 91 to 100 of about 279,299 (375)

Prognostic value of worsening renal function in outpatients with chronic heart failure [PDF]

, 2014
Introduction and objectives: Renal function impairment predicts poor survival in heart failure. Attention has recently shifted to worsening renal function, based mostly on serum creatinine and estimated glomerular filtration rate.
Azevedo, A, Bettencourt, P, Couto, M, Frioes, F, Laszczynska, O, Pimentel, R   +5 more
core   +1 more source

Label‐Free Dual‐Modal Photoacoustic/Ultrasound Localization Imaging for Studying Acute Kidney Injury

Advanced Science, EarlyView.
This work develops a 3D label‐free photoacoustic/super‐resolution ultrasound imaging system as a comprehensive non‐invasive tool for acute kidney injury (AKI) study. This technique visualizes the intricate structure of renal microvessels and provides critical physiological insights, including renal hemodynamics and oxygenation.
Shensheng Zhao, Xingxing Zhang, Keith Bailey, Sathvik Pai, Yang Zhao, Yun‐Sheng Chen   +5 more
wiley   +1 more source

MEASUREMENT OF ESTIMATED GLOMERULAR FILTRATION RATE IS USEFUL IN STROKE PATIENTS [PDF]

, 2014
弘前大学博士（保健学）背景：慢性腎臓病（CKD）は世界的な公衆衛生的問題であり、CKD は脳卒中発症の 危険因子であることが明らかとなっているが、脳卒中患者の腎機能を評価することは 一般に困難である。 目的：本研究は、脳卒中患者の腎機能評価に推定糸球体濾過率（eGFR）を用いるこ との妥当性を明らかにすることを目的とした。 対象と方法：対象は脳卒中で545 例である。分析は、 eGFR と生化学的データ、高血 圧症、糖尿病、高コレステロール血症、心房細動の有病率との関連を評価した。 結果： 178 名 ...
Kitajima, Yu
core   +3 more sources

Prognostic impact of postoperative fixed‐point inflammation in patients with gastric cancer after curative gastrectomy: A validation cohort study

Annals of Gastroenterological Surgery, EarlyView.
The cutoff value of CRP by sex for poor OS remains unclear. This study aimed to determine the cutoff values of CRP on postoperative day 3 to predict poor OS in men and women with gastric cancer after radical gastrectomy. The high‐CRP group has poorer overall survival than the low‐CRP group for gastric cancer after gastrectomy.
Ryota Matsui, Manabu Ohashi, Motonari Ri, Rie Makuuchi, Tomoyuki Irino, Masaru Hayami, Takeshi Sano, Souya Nunobe   +7 more
wiley   +1 more source

Estimated glomerular filtration rate and the risk–benefit profile of intensive blood pressure control amongst nondiabetic patients: a post hoc analysis of a randomized clinical trial

Journal of Internal Medicine, 2018
The Systolic Blood Pressure Intervention Trial (SPRINT; ClinicalTrials.gov, NCT01206062) reported reduced cardiovascular events by intensive blood pressure (BP) control amongst hypertensive patients without diabetes.
Y. Obi, Kamyar Kalantar-Zadeh, Kamyar Kalantar-Zadeh, A. Shintani, C. Kovesdy, Takayuki Hamano   +5 more
semanticscholar   +1 more source

Performance of formulae based estimates of glomerular filtration rate for carboplatin dosing in stage 1 seminoma [PDF]

, 2014
<b>Background:</b> Single cycle carboplatin, dosed by glomerular filtration rate (GFR), is standard adjuvant therapy for stage 1 seminoma. Accurate measurement of GFR is essential for correct dosing.
Forte, Carla, Gillen, Gerry, MacPherson, Iain R., Mark, Patrick B., Morrison, Paula, Shepherd, Scott T.C., White, Jeff D.   +6 more
core   +1 more source

A Recombinant Antibody Against ALK2 Promotes Tissue Iron Redistribution and Contributes to Anemia Resolution in a Mouse Model of Anemia of Inflammation

American Journal of Hematology, Volume 100, Issue 5, Page 797-812, May 2025.
ABSTRACT Patients with chronic inflammation are burdened with anemia of inflammation (AI), where inflammatory cytokines inhibit erythropoiesis, impede erythropoietin production, and limit iron availability by inducing the iron regulator hepcidin. High hepcidin hinders iron absorption and recycling, thereby worsening the impaired erythropoiesis by ...
Chia‐Yu Wang, Emiliano Melgar‐Bermudez, Diana Welch, Kevin B. Dagbay, Seemana Bhattacharya, Evan Lema, Tyler Daman, Olivia Sierra, Radina Todorova, Papa Makhtar Drame, Rosa Grenha, Ffolliott M. Fisher, Dena Grayson, Lorena Lerner, Samuel M. Cadena, Jasbir Seehra, Jennifer Lachey   +16 more
wiley   +1 more source

Increasing Mortality in Adults With Diabetes and Low Estimated Glomerular Filtration Rate in the Absence of Albuminuria

Diabetes Care, 2018
OBJECTIVE Improved blood pressure control and use of renin-angiotensin-aldosterone system blockers have altered the clinical presentation or phenotype of chronic kidney disease (CKD) in U.S. adults with diabetes.
H. Kramer, Robert E Boucher, D. Leehey, L. Fried, Guo Wei, T. Greene, S. Rosas, R. Cooper, G. Cao, S. Beddhu   +9 more
semanticscholar   +1 more source

Comparing Results of Five Glomerular Filtration Rate-Estimating Equations in the Korean General Population. MDRD Study, Revised Lund-Malmö, and Three CKD-EPI Equations [PDF]

, 2016
Estimated glomerular filtration rate (eGFR) is a widely used index of kidney function. Recently, new formulas such as the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations or the Lund-Malmö equation were introduced for assessing eGFR.
Han-Ik Cho, Hyesun Kim, Hyun Suk Yang, Mina Hur, Misuk Ji, null null, Salvatore Di Somma, Silvia Navarin, Yoon-Hee Lee   +8 more
core   +1 more source

Pyruvate Kinase Function Correlates With Red Blood Cell Properties and Clinical Manifestations in Sickle Cell Disease

American Journal of Hematology, Volume 100, Issue 5, Page 785-796, May 2025.
ABSTRACT Pyruvate kinase (PK) is a key enzyme involved in the final step of glycolysis, essential to produce adenosine triphosphate (ATP). Relatively decreased red blood cell (RBC) PK activity (reflected by a lower PK/hexokinase [HK] ratio) and PK thermostability (PK activity after exposure to heat) were recently identified as pathophysiological ...
M. J. M. Traets, J. F. Bos, S. van der Veen, L. van Pelt, M. J. van Dijk, B. A. van Oirschot, J. R. A. de Wilde, J. J. Jans, W. W. van Solinge, S. E. M. Schols, M. N. Lauw, M. H. Cnossen, E. Nur, B. J. Biemond, A. W. Rijneveld, E. J. van Beers, R. van Wijk, M. A. E. Rab   +17 more
wiley   +1 more source