Results 161 to 170 of about 279,299 (375)

Comparison of 2 Methods for the Calculation of Estimated Glomerular Filtration Rate [PDF]

open access: bronze, 2007
Giuseppe Lippi   +3 more
openalex   +1 more source

Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis

open access: yesThe Lancet, 2010
K. Matsushita   +7 more
semanticscholar   +1 more source

First‐in‐Human Phase 1 Study to Evaluate the Clinical Pharmacology Properties of RBN‐3143, a Novel Inhibitor of Mono‐Adenosine Diphosphate Ribosyltransferase‐PARP14

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract RBN‐3143 is an inhibitor of PARP14 in development for inflammatory diseases. Multiple assessments were conducted to evaluate the clinical pharmacology properties of RBN‐3134. A randomized, double‐blind, placebo‐controlled study assigned healthy volunteers (HVs) to single ascending doses (SADs) (25‐1000 mg) or multiple ascending doses (MADs ...
Thomas M. Polasek   +9 more
wiley   +1 more source

Expressing the Modification of Diet in Renal Disease Study Equation for Estimating Glomerular Filtration Rate with Standardized Serum Creatinine Values [PDF]

open access: bronze, 2007
Andrew S. Levey   +6 more
openalex   +1 more source

Characterization and implications of the initial estimated glomerular filtration rate 'dip' upon sodium-glucose co-transporter-2 inhibition with empagliflozin in the EMPA-REG OUTCOME trial.

open access: yesKidney International, 2020
B. Kraus   +12 more
semanticscholar   +1 more source

A Systematic Review of the Costs of Drug‐Associated Acute Kidney Injury and Potential Cost Savings With Nephrotoxin Stewardship Prevention Strategies

open access: yesClinical Pharmacology &Therapeutics, Volume 117, Issue 4, Page 989-1004, April 2025.
There is a scarcity of information related to the financial impact of acute kidney injury (AKI), and even more so the economics of drug‐associated AKI (D‐AKI). Our goal was to provide a comprehensive summary of the economic burden of D‐AKI by evaluating the costs of D‐AKI compared to not developing AKI and cost savings associated with nephrotoxin ...
Britney A. Stottlemyer   +3 more
wiley   +1 more source

Primary care-based disease management of chronic kidney disease (CKD), based on estimated glomerular filtration rate (eGFR) reporting, improves patient outcomes [PDF]

open access: bronze, 2007
N. Richards   +9 more
openalex   +1 more source

Insights from CREDENCE trial indicate an acute drop in estimated glomerular filtration rate during treatment with canagliflozin with implications for clinical practice.

open access: yesKidney International, 2020
M. Oshima   +19 more
semanticscholar   +1 more source

Pharmacokinetic Modeling and Model‐Based Hypothesis Generation for Dose Optimization of Clonidine in Neonates With Neonatal Opioid Withdrawal Syndrome

open access: yesClinical Pharmacology &Therapeutics, Volume 117, Issue 5, Page 1254-1263, May 2025.
The No‐POPPY study (NCT03396588), a double‐blind, randomized trial compared morphine with clonidine therapy for neonatal opioid withdrawal syndrome (NOWS) and found that the duration of treatment was similar across groups. This is significant because perinatal use of morphine has the potential for neurodevelopmental consequences.
Fei Tang   +4 more
wiley   +1 more source

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