Results 71 to 80 of about 221,285 (352)

The Variability of Estimated Glomerular Filtration Rate Decline in Alport Syndrome

Canadian Journal of Kidney Health and Disease, 2016
Background: A progressive trajectory toward renal failure is common in patients with Alport syndrome. Genotype-phenotype correlations have been well described; however, the natural history of the trajectory toward renal failure is not well described ...
David Langsford, Mila Tang, Ognjenka Djurdjev, Lee Er, Adeera Levin   +4 more
doaj   +1 more source

Association between serum bilirubin and estimated glomerular filtration rate among elderly persons. [PDF]

PLoS ONE, 2014
Chronic kidney disease (CKD) is a major public health problem. However, few studies have examined the significance of serum bilirubin as a risk factor for the development of CKD in the general Japanese population. The subjects comprised 413 men (mean age:
Ryuichi Kawamoto, Daisuke Ninomiya, Yoichi Hasegawa, Yoshihisa Kasai, Tomo Kusunoki, Nobuyuki Ohtsuka, Teru Kumagi   +6 more
doaj   +1 more source

Long-term lithium treatment in bipolar disorder. effects on glomerular filtration rate and other metabolic parameters [PDF]

, 2017
.BACKGROUND: Concerns about potential adverse effects of long-term exposure to lithium as a mood-stabilizing treatment notably include altered renal function.
Abramowicz, Maria, Alda, Martin, Baldessarini, Ross J., Bauer, Michael, Bocchetta, Alberto, Bolzani, Lorenza, Calkin, Cynthia V, Chillotti, Caterina, Hidalgo Mazzei, Diego, Manchia, Mirko, Murru, Andrea, Müller Oerlinghausen, Bruno, Perugi, Giulio, Pinna, Marco, Quaranta, Giuseppe, Reginaldi, Daniela, Reif, Andreas, Ritter, Philipp, Rybakowski, Janusz K, Saiger, David, SANI, Gabriele, Selle, Valerio, Stamm, Thomas, Tondo, Leonardo, Vázquez, Gustavo H, Veeh, Julia, Vieta, Eduard   +26 more
core   +3 more sources

Renal Function - Estimation of Glomerular Filtration Rate [PDF]

Journal of Medical Biochemistry, 2007
Funkcija Bubrega - Procena Brzine Glomerularne Filtracije Brzina glomerularne filtracije (GFR) je široko prihvaćena kao najbolja opšta mera funkcije bubrega. Vodiči američke Nacionalne fondacije za bubreg definišu hroničnu bubrežnu bolest (HBB) bilo sa vrednošću GFR koja je manja od 60 mL/min/1,73 m2 ili sa prisustvom oštećenja bubrega, bez ...
Dajak, Marijana, Ignjatović, Svetlana, Majkić-Singh, Nada   +2 more
openaire   +2 more sources

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

Advanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren, Renhe Cao, Xiaoshan Ye, Wenbin Pang, Qingshang Bi, Meihui Huang, Qionglin Zhou, Dan Ye, Wei Xiang, Le Xiao   +9 more
wiley   +1 more source

Comparison of the Effects of Telbivudine and Entecavir Treatment on Estimated Glomerular Filtration Rate in Patients with Chronic Hepatitis B

Gut and Liver, 2015
Background/AimsThe aim of this study was to evaluate the estimated glomerular filtration rate (eGFR) during telbivudine (LdT) versus entecavir (ETV) treatment in chronic hepatitis B (CHB) patients with underlying comorbidities such as diabetes mellitus ...
doaj   +1 more source

Mapping Satellite Glial Cell Heterogeneity Reveals Distinct Spatial Organization and Implies Functional Diversity in the Dorsal Root Ganglion

Advanced Science, EarlyView.
Four distinct satellite glial cell subtypes are identified in mouse dorsal root ganglia using single‐cell RNA sequencing and spatial validation. These subtypes show unique marker profiles and anatomical distributions. Human dorsal root ganglia display layered perisomatic organization with differential marker expression.
Ole Andreas Ahlgreen, Mads Würgler Hansen, Jonas Baake, Thomas Engelbrecht Hybel, Rachele Rossi, Xin Lai, Ishwarya Sankaranarayanan, Johanne Amalie Pold, Lin Lin, Line Reinert, Søren Riis Paludan, Theodore John Price, Lone Tjener Pallesen, Christian Bjerggaard Vægter   +13 more
wiley   +1 more source

Patient safety and estimation of renal function in patients prescribed new oral anticoagulants for stroke prevention in atrial fibrillation [PDF]

, 2013
OBJECTIVE: In clinical trials of dabigatran and rivaroxaban for stroke prevention in atrial fibrillation (AF), drug eligibility and dosing were determined using the Cockcroft-Gault equation to estimate creatine clearance as a measure of renal function ...
Ashman, N, Green, L, Hull, SA, MacCallum, PK, Mathur, R, Morris, JK, Saja, K   +6 more
core   +3 more sources

Prediction of Glomerular Filtration Rate in Cancer Patients by an Equation for Japanese Estimated Glomerular Filtration Rate [PDF]

Japanese Journal of Clinical Oncology, 2013
Assessment of renal function is important for safe cancer chemotherapy, and eligibility criteria for clinical trials often include creatinine clearance. However, creatinine clearance overestimates glomerular filtration rate, and various new formulae have been proposed to estimate glomerular filtration rate.
Yohei, Funakoshi, Yutaka, Fujiwara, Naomi, Kiyota, Toru, Mukohara, Takanobu, Shimada, Masanori, Toyoda, Yoshinori, Imamura, Naoko, Chayahara, Michio, Umezu, Naoki, Otsuki, Ken-ichi, Nibu, Hironobu, Minami   +11 more
openaire   +2 more sources

Tubule‐Derived IFN‐α Promotes GSDMD‐Mediated Macrophage Pyroptosis to Drive Renal Inflammation and Fibrosis Through JAK2/STAT2 Activation

Advanced Science, EarlyView.
Mao and colleagues uncover a STAT2/IRF9‐dependent signaling axis through which tubular epithelial cell (TEC)‐derived IFN‐α induces gasdermin D (GSDMD)‐mediated pyroptosis in macrophages. This TEC‐macrophage feedback loop amplifies renal inflammation and fibrosis, providing mechanistic insight into the progression of chronic kidney disease and revealing
Yiping Xu, Yating Wang, Siming Jiang, Yi Li, Guanglan Li, Yuchu Liu, Siyuan Li, Yiming Zhou, Qinghua Liu, Yi Zhou, Wei Chen, Hongyu Li, Haiping Mao   +12 more
wiley   +1 more source