Results 71 to 80 of about 279,299 (375)
Objective Granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) are chronic life‐threatening vasculitides requiring substantial immunotherapy. Adult trials identified rituximab (RTX) as an alternative to cyclophosphamide (CYC) for remission induction of GPA and MPA.
Samuel J. Gagne+27 more
wiley +1 more source
The Variability of Estimated Glomerular Filtration Rate Decline in Alport Syndrome
Background: A progressive trajectory toward renal failure is common in patients with Alport syndrome. Genotype-phenotype correlations have been well described; however, the natural history of the trajectory toward renal failure is not well described ...
David Langsford+4 more
doaj +1 more source
OBJECTIVE To characterize long-term kidney disease trajectories in persons with and without diabetes in a general population. RESEARCH DESIGN AND METHODS We classified 15,517 participants in the community-based Atherosclerosis Risk in Communities (ARIC ...
B. Warren+6 more
semanticscholar +1 more source
Estimated glomerular filtration rate and risk of poor outcomes after stroke [PDF]
We thank the data team of the Norfolk and Norwich University Hospital Stroke Services.Peer ...
Barlas, Raphae S.+6 more
core +2 more sources
Relationship Between Gout Flare States and Patient‐Reported Outcomes After Allopurinol Initiation
Objective Gout flares are the most important clinical feature of the disease. A hypothetical maximum flare occurrence in the preceding six months has been suggested to be no flares for a patient‐acceptable symptom state (PASS) and only one flare for low disease activity (LDA).
Lisa K. Stamp+6 more
wiley +1 more source
Rationale & Objective: Use of cystatin C in addition to creatinine to estimate glomerular filtration rate (estimated glomerular filtration rate based on cystatin C [eGFRcys] and estimated glomerular filtration rate based on creatinine [eGFRcr ...
Yeli Wang+14 more
doaj
Cystatin C-derived estimated glomerular filtration rate in children with sickle cell anaemia
Background Sickle cell disease is the most common inherited blood disorder in humans and constitutes a major public health burden. It is a multisystemic condition with long-term renal complications.
Hakeem Edun Babatunde+5 more
doaj +1 more source
The accuracy of the estimated glomerular filtration rate (eGFR) in cancer patients is very important for dose adjustments of anti-malignancy drugs to reduce toxicities and enhance therapeutic outcomes.
W. Chancharoenthana+4 more
semanticscholar +1 more source
A New Equation to Estimate Glomerular Filtration Rate [PDF]
Equations to estimate glomerular filtration rate (GFR) are routinely used to assess kidney function. Current equations have limited precision and systematically underestimate measured GFR at higher values.To develop a new estimating equation for GFR: the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation.Cross-sectional analysis with ...
Josef Coresh+10 more
openaire +3 more sources
Objective The objective of this study was to evaluate and compare the risk of hepatotoxicity associated with the use of febuxostat and benzbromarone in patients with gout. Methods New users of febuxostat or benzbromarone with monitoring of liver function at least three times in a year after initiation of the study drugs were identified from an ...
Wenyan Sun+8 more
wiley +1 more source