Results 61 to 70 of about 2,627,208 (304)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A Framework for Estimating the Value of Deterrence.
International Topical Meeting on Probabilistic Safety Assessment and Analysis (PSA 2019) Charleston, SC, April 28-May 3, 2019. International Topical Meeting on Probabilistic Safety Assessment and Analysis (2019 : Charleston, S.C.), 2022 This paper presents a framework for calculating the value of deterrence related to countermeasures implemented to mitigate an attack by an adaptive adversary. We offer a methodology for adapting Defender-Attacker Decision Trees to partition the utility of countermeasures into three components: (1) threat reduction (deterrence), (2) vulnerability ...
John, Richard S. +3 more
openaire +2 more sources
Estimated hedonic wage function and value of life in an African country [PDF]
This paper reports the first study of compensating wage differentials for work-related fatalities in an African country. Using original data from the 2002 Tunisian Caisse nationale de la sécurité sociale, statistically significant compensating wage ...
Mohamed Ayadi +2 more
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
An Estimated Small Open Economy Model of the Financial Accelerator [PDF]
This paper develops a small open economy model in which entrepreneurs partially finance investment using foreign currency-denominated debt subject to an external finance premium. We use Bayesian estimation techniques to evaluate the importance of balance
Selim Elekdag +2 more
core
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
The value of estimating urinary indican.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1972 Urinary indican, a metabolic product of bacterial action on tryptophan in the small bowel, has been estimated in the urine as an indirect indication of small bowel bacterial contamination, in 50 normal controls, 18 patients with small bowel disease, 22 patients with calcific pancrea~itis and group of 20 children with kwashiorkor and 10 control ...
Novis, B.H. +3 more
openaire +3 more sources
Estimated value of category based on extensiveness of category beliefs.
, 2014 Estimated value of category based on extensiveness of category beliefs.
Inna Galperin (587828) +1 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
On consistent estimation of dimension values
Journal of Multivariate AnalysisThe problem of estimating, from a random sample of points, the dimension of a compact subset $S$ of the Euclidean space is considered. The emphasis is put on consistency results in the statistical sense. That is, statements of convergence to the true dimension value when the sample size grows to infinity.
Alejandro Cholaquidis +2 more
openaire +2 more sources