Results 71 to 80 of about 2,627,208 (304)

Effects of Disease Type and Latency on the Value of Mortality Risk [PDF]

open access: yes
We evaluate the effects of disease type and latency on willingness to pay (WTP) to reduce environmental risks of chronic, degenerative disease. Using contingent-valuation data collected from approximately 1,200 respondents in Taiwan, we find that WTP ...
Jin-Tan Liu, James K. Hammitt
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

CALCULATION METHOD OF COMPANY FULL LOAN VALUE TAKING INTO ACCOUNT INCOMING CASH FLOWS

open access: yesФінансово-кредитна діяльність: проблеми теорії та практики, 2018
Financial intermediaries with the purpose to sale effectively their loan products successfully combine credit a reduced interest rate on the loan and increased commission, compensate expenses at the expense of insurance companies, raised rates for cash ...
O. Dobrovolskij
doaj   +1 more source

LEAST ABSOLUTE VALUE ESTIMATION

open access: yesJournal of the Operations Research Society of Japan, 1997
Summary: This research first describes historical perspectives of Least Absolute Value (LAV) estimation, which has been long considered as an estimation alternative of conventional Least Squares (LS) regression. Then, this article explores statistical properties regarding the LAV estimation from Goal Programming (GP). Using a small illustrative example,
openaire   +3 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Spatial and Temporal Dynamics and Value of Nature-Based Recreation, Estimated via Social Media.

open access: yesPLoS ONE, 2016
Conserved lands provide multiple ecosystem services, including opportunities for nature-based recreation. Managing this service requires understanding the landscape attributes underpinning its provision, and how changes in land management affect its ...
Laura J Sonter   +3 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Estimation of value at risk: extreme value and robust approaches [PDF]

open access: yesOperations Research and Decisions, 2010
Summary: The large portfolios of traded assets held by many financial institutions have made the measurement of market risk a necessity. In practice, VaR measures are computed for several holding periods and confidence levels. A key issue in implementing VaR and related risk measures is to obtain accurate estimates for the tails of the conditional ...
Trzpiot, Grażyna, Majewska, Justyna
openaire   +2 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Home - About - Disclaimer - Privacy