Results 71 to 80 of about 9,777,519 (250)

Genomic Prediction for 25 Agronomic and Quality Traits in Alfalfa (Medicago sativa)

open access: yesFrontiers in Plant Science, 2018
Agronomic and quality traits in alfalfa are very important to forage industry. Genomic prediction (GP) based on genotyping-by-sequencing (GBS) data could shorten the breeding cycles and accelerate the genetic gains of these complex traits, if they ...
Congjun Jia   +7 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Post lung-transplant predictive value of thermodilution vs estimated Fick cardiac output measurement

open access: yesJHLT Open
Background: Comparison of thermodilution (TD) and indirect Fick (iFick) methods of cardiac output (CO) measurement has not been well described in patients with World Health Organization (WHO) group 3 pulmonary hypertension (PH).
Jose Rivera-Robles, MD   +7 more
doaj   +1 more source

THE VALUE OF SPORT FISHING IN THE SNAKE RIVER BASIN OF CENTRAL IDAHO [PDF]

open access: yes
The value of sportfishing in the Snake River Basin in Central Idaho was measured using a two-stage/disequilibrium travel model. The two-stage/disequilibrium model does not require monetization of recreationists?
Taylor, R. Garth   +2 more
core  

Kernel-estimated Nonparametric Overlap-Based Syncytial Clustering [PDF]

open access: yes, 2018
Standard clustering algorithms usually find regular-structured clusters such as ellipsoidally- or spherically-dispersed groups, but are more challenged with groups lacking formal structure or definition. Syncytial clustering is the name that we introduce
Maitra, Ranjan   +1 more
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Accrual of Estimated Reserves and Estimated Liabilities and their Impact on Financial Results in the Accounting (Financial) Statements of Enterprises

open access: yesУчёт. Анализ. Аудит
The purpose of the study is to consider the problems of formation of the valuation of estimated reserves falling under the requirement of FAS 5/2019 “Reserves” the contracts (orders) recognized as obviously unprofitable or loss-making after their ...
N. S. Suleymanov
doaj   +1 more source

Description and estimated value of the model parameters ([30, 31]).

open access: yes, 2018
Description and estimated value of the model parameters ([30, 31]).
Andrés Anzo-Hernández (4846333)   +4 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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