Results 71 to 80 of about 9,777,519 (250)
Genomic Prediction for 25 Agronomic and Quality Traits in Alfalfa (Medicago sativa)
Agronomic and quality traits in alfalfa are very important to forage industry. Genomic prediction (GP) based on genotyping-by-sequencing (GBS) data could shorten the breeding cycles and accelerate the genetic gains of these complex traits, if they ...
Congjun Jia +7 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Post lung-transplant predictive value of thermodilution vs estimated Fick cardiac output measurement
Background: Comparison of thermodilution (TD) and indirect Fick (iFick) methods of cardiac output (CO) measurement has not been well described in patients with World Health Organization (WHO) group 3 pulmonary hypertension (PH).
Jose Rivera-Robles, MD +7 more
doaj +1 more source
THE VALUE OF SPORT FISHING IN THE SNAKE RIVER BASIN OF CENTRAL IDAHO [PDF]
The value of sportfishing in the Snake River Basin in Central Idaho was measured using a two-stage/disequilibrium travel model. The two-stage/disequilibrium model does not require monetization of recreationists?
Taylor, R. Garth +2 more
core
Kernel-estimated Nonparametric Overlap-Based Syncytial Clustering [PDF]
Standard clustering algorithms usually find regular-structured clusters such as ellipsoidally- or spherically-dispersed groups, but are more challenged with groups lacking formal structure or definition. Syncytial clustering is the name that we introduce
Maitra, Ranjan +1 more
core
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
The purpose of the study is to consider the problems of formation of the valuation of estimated reserves falling under the requirement of FAS 5/2019 “Reserves” the contracts (orders) recognized as obviously unprofitable or loss-making after their ...
N. S. Suleymanov
doaj +1 more source
Description and estimated value of the model parameters ([30, 31]).
Description and estimated value of the model parameters ([30, 31]).
Andrés Anzo-Hernández (4846333) +4 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source

