Results 201 to 210 of about 67,818,891 (245)

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

The effectiveness of the communities that HEAL intervention on reducing non-fatal opioid overdoses: A prespecified secondary analysis of a waitlist cluster control randomized controlled trial. [PDF]

Int J Drug Policy
Gilbert L, Chahine R, Chandler R, Feaster DJ, Kim E, Aldridge A, Bagley S, Balvanz P, Fernandez S, Rock P, Vickers-Smith RA, Villani J, Battaglia T, Brown J, Bush H, Chase RP, Collins T, D'Costa L, Damato-MacPherson C, David JL, Defiore-Hyrmer J, Freeman PR, Glasgow L, Hammerslag LR, Hotchkiss J, Hunt T, Hussain S, Kamanu V, Knott C, Knudsen HK, LaRochelle M, Laudate A, Lyons M, McMullan J, Nakayima J, Schackman BR, Slavova S, Tan S, Vandergrift N, Walters ST, Westgate PM, Wu E, Young AM, Zarkin GA, Freisthler B, Oga E, Samet JH, Walsh SL, Winhusen J, Jackson R, El-Bassel N.   +50 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Urban Climate Risk Governance and Corporate Energy Intensity: Evidence From China's Climate Adaptation City Pilots. [PDF]

Ann N Y Acad Sci
Liang S, Long Y, Xiao J, Lu X, Chen D.
europepmc   +1 more source

Cartesian equivariant representations for learning and understanding molecular orbitals. [PDF]

Proc Natl Acad Sci U S A
King DS, Grzenda D, Zhu R, Hudson N, Foster I, Cheng B, Gagliardi L.   +6 more
europepmc   +1 more source

An explainable AI framework for enhanced software defect prediction using transformer-assisted boosting. [PDF]

Sci Rep
Kun Q, Shaikh ZA, Yang J, Kumar G, Mohammed HA, Yee PL.   +5 more
europepmc   +1 more source

Public contributions to the development of antibiotics: two successful and two failed investments. [PDF]

J Pharm Policy Pract
Schmidt L, Sehic O, Theuretzbacher U, Wild C.   +3 more
europepmc   +1 more source

More concentrated precipitation decreases terrestrial water storage. [PDF]

Nature
Lesk CS, Mankin JS.
europepmc   +1 more source

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Estimates of character sums in finite fields

Mathematical Notes, 2010
Suppose \(p\) is a prime and \(\{\omega_1,\dots,\omega_n\}\) is a basis of \(\mathbb F_{p^n}\) over \(\mathbb F_p\). Suppose \(B\) is an \(n\)-dimensional parallelepiped with edges \(H_1,\dots,H_n\), that is \[ B=\left\{\sum_{x=1}^n x_i\omega_i:N_i+1\leq x_i\leq N_i+H_i, i=1,\dots,n\right\}, \] where \(0\leq N_i0\), there is a natural number \(k ...
S V Konyagin
exaly   +2 more sources