Results 51 to 60 of about 84,599 (243)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

On Some Dynamical Systems in Finite Fields and Residue Rings

, 2007
We use character sums to confirm several recent conjectures of V. I. Arnold on the uniformity of distribution properties of a certain dynamical system in a finite field. On the other hand, we show that some conjectures are wrong.
Shparlinski, Igor E.
core   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Computing Dirichlet character sums to a power-full modulus

, 2014
The Postnikov character formula is used to express large portions of a Dirichlet character sum in terms of quadratic exponential sums. The quadratic sums are then computed using an analytic algorithm previously derived by the author.
Hiary, Ghaith A.
core   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Exponential sums and polynomial congruences in two variables: the quasi-homogeneous case [PDF]

, 2012
We adapt ideas of Phong, Stein and Sturm and ideas of Ikromov and M\"uller from the continuous setting to various discrete settings, obtaining sharp bounds for exponential sums and the number of solutions to polynomial congruences for general quasi ...
Wright, James
core   +1 more source

Bounds of triple exponential sums with mixed exponential and linear terms

, 2018
We establish bounds of triple exponential sums with mixed exponential and linear function. The method we use is by Shparlinski together with a bound of additive energy from Roche-Newton, Rudnev and Shkredov.Comment: Corrected a ...
Yau, Kam Hung
core   +1 more source

Estimates of character sums with exponential function [PDF]

Acta Arithmetica, 2001
Let \(n \geq 2\) and \(\lambda\) be integers satisfying \((n, \lambda)=1\) and \(\lambda\) belonging to the exponent \(d\) modulo \(n\). Given a primitive Dirichlet character \(\chi\) mod \(n\) the author proves the estimate \[ \left|\sum_{x=1}^X \chi(a \lambda^x +b) \right|< \sqrt{n} \left( \frac{2}{\pi} \log n + \frac{7}{5} \right).
openaire   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source