Results 91 to 100 of about 1,204,720 (271)

Approach to Equilibrium for a Forced Burgers Equation [PDF]

open access: yesarXiv, 2001
We show that approach to equilibrium in certain forced Burgers equations is implied by a decay estimate on a suitable intrinsic semigroup estimate, and we verify this estimate in a variety of cases including a periodic force.
arxiv  

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Strichartz estimates for the kinetic transport equation [PDF]

open access: yesarXiv, 2009
We prove Strichartz estimates for the kinetic transport equation. Our results extend considerably the known in the literature range of the Strichartz estimates for that equation.
arxiv  

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

%QLS SAS Macro: A SAS Macro for Analysis of Correlated Data Using Quasi-Least Squares

open access: yesJournal of Statistical Software, 2010
Quasi-least squares (QLS) is an alternative computational approach for estimation of the correlation parameter in the framework of generalized estimating equations (GEE). QLS overcomes some limitations of GEE that were discussed in Crowder (1995).
Han-Joo Kim, Justine Shults
doaj  

Sparse Estimation for Hamiltonian Mechanics

open access: yesMathematics
Estimating governing equations from observed time-series data is crucial for understanding dynamical systems. From the perspective of system comprehension, the demand for accurate estimation and interpretable results has been particularly emphasized ...
Yuya Note   +4 more
doaj   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

Scaling bounds on dissipation in turbulent flows

open access: yes, 2015
We present a new rigorous method for estimating statistical quantities in fluid dynamics such as the (average) energy dissipation rate directly from the equations of motion.
Seis, Christian
core   +1 more source

Carleman and Observability Estimates for Stochastic Wave Equations [PDF]

open access: yesarXiv, 2007
Based on a fundamental identity for stochastic hyperbolic-like operators, we derive in this paper a global Carleman estimate (with singular weight function) for stochastic wave equations. This leads to an observability estimate for stochastic wave equations with non-smooth lower order terms.
arxiv  

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