Results 71 to 80 of about 1,131,580 (326)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Outage Detection for Distribution Networks Using Limited Number of Power Flow Measurements

open access: yesJournal of Modern Power Systems and Clean Energy, 2020
Accurate topology estimation is crucial for effectively operating modern distribution networks. Line outages in a distribution network change the network topology by disconnecting some parts of the network from the main grid.
Basel Alnajjab   +5 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Wavelet Based Semi-blind Channel Estimation For Multiband OFDM

open access: yes, 2007
This paper introduces an expectation-maximization (EM) algorithm within a wavelet domain Bayesian framework for semi-blind channel estimation of multiband OFDM based UWB communications.
Duhamel, Pierre   +3 more
core   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

A Novel Gaussian Particle Swarms optimized Particle Filter Algorithm for the State of Charge Estimation of Lithium-ion Batteries

open access: yesInternational Journal of Electrochemical Science, 2020
A gaussian particle swarm optimized particle filter estimation method, along with the second-order resistance-capacitance model, is proposed for the state of charge estimation of lithium-ion battery in electric vehicles.
Xinyang Wang   +5 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Low-complexity variable step-size sign algorithm based on Weibull distribution function

open access: yesDianxin kexue, 2018
The performance of the traditional second-order statistics based channel estimation methods degrade seriously in the presence of impulsive noises.In order to deal with this problem,a Weibull distribution function based variable step-size sign algorithm ...
Rui ZHANG   +3 more
doaj   +2 more sources

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Locating critical sliding surface of slopes by estimation of distribution algorithm

open access: yesShuiwen dizhi gongcheng dizhi
Most of the optimization algorithms to solve the slope critical sliding surface have the disadvantages of complex structure, difficult to determine the parameter value, and poor optimization effect.
Qiuling LYU, Jianping WU, Donglin WANG
doaj   +1 more source

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