Results 51 to 60 of about 1,087,874 (283)

Rule Induction by Estimation of Distribution Algorithms

, 2002
In this chapter a preliminary work on the use of Estimation of Distribution Algorithms (EDAs) for the induction of classification rules is presented. Each individual obtained by simulation of the probability distribution learnt in each EDA generation represents a disjunction of a finite number of simple rules.
Sierra Araujo, Basilio, Jiménez, E.A., Inza Cano, Iñaki, Larrañaga Múgica, Pedro María, Muruzábal Sanz, Jorge   +4 more
openaire   +2 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

STUDI PERBANDINGAN ANTARA ALGORITMA BIVARIATE MARGINAL DISTRIBUTION DENGAN ALGORITMA GENETIKA

Jurnal Informatika, 2006
Bivariate Marginal Distribution Algorithm is extended from Estimation of Distribution Algorithm. This heuristic algorithm proposes the new approach for recombination of generate new individual that without crossover and mutation process such as genetic ...
Chastine Fatichah, Imam Artha Kusuma, Yudhi Purwananto   +2 more
doaj  

Moving Point Density Estimation Algorithm Based on a Generated Bayesian Prior

ISPRS International Journal of Geo-Information, 2015
To improve decision making, real-time population density must be known. However, calculating the point density of a huge dataset in real time is impractical in terms of processing time. Accordingly, a fast algorithm for estimating the distribution of the
Akinori Asahara, Hideki Hayashi, Takashi Kai   +2 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Adaptive independent Metropolis--Hastings

, 2009
We propose an adaptive independent Metropolis--Hastings algorithm with the ability to learn from all previous proposals in the chain except the current location. It is an extension of the independent Metropolis--Hastings algorithm.
Hauge, Ragnar, Holden, Lars, Holden, Marit   +2 more
core   +1 more source

Regularized continuous estimation of distribution algorithms

Applied Soft Computing, 2013
Regularization is a well-known technique in statistics for model estimation which is used to improve the generalization ability of the estimated model. Some of the regularization methods can also be used for variable selection that is especially useful in high-dimensional problems.
Karshenas, Hossein, Santana Hermida, Roberto, Bielza Lozoya, María Concepción, Larrañaga Múgica, Pedro María   +3 more
openaire   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Sub-structural niching in estimation of distribution algorithms [PDF]

Proceedings of the 7th annual conference on Genetic and evolutionary computation, 2005
We propose a sub-structural niching method that fully exploits the problem decomposition capability of linkage-learning methods such as the estimation of distribution algorithms and concentrate on maintaining diversity at the sub-structural level.
Sastry, K., Abbass, H. A., Goldberg, D. E., Johnson, D. D.   +3 more
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source