Results 71 to 80 of about 1,087,874 (283)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Outage Detection for Distribution Networks Using Limited Number of Power Flow Measurements

open access: yesJournal of Modern Power Systems and Clean Energy, 2020
Accurate topology estimation is crucial for effectively operating modern distribution networks. Line outages in a distribution network change the network topology by disconnecting some parts of the network from the main grid.
Basel Alnajjab   +5 more
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

A Novel Gaussian Particle Swarms optimized Particle Filter Algorithm for the State of Charge Estimation of Lithium-ion Batteries

open access: yesInternational Journal of Electrochemical Science, 2020
A gaussian particle swarm optimized particle filter estimation method, along with the second-order resistance-capacitance model, is proposed for the state of charge estimation of lithium-ion battery in electric vehicles.
Xinyang Wang   +5 more
doaj   +1 more source

ecp: An R Package for Nonparametric Multiple Change Point Analysis of Multivariate Data [PDF]

open access: yes, 2013
There are many different ways in which change point analysis can be performed, from purely parametric methods to those that are distribution free. The ecp package is designed to perform multiple change point analysis while making as few assumptions as ...
James, Nicholas A., Matteson, David S.
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Low-complexity variable step-size sign algorithm based on Weibull distribution function

open access: yesDianxin kexue, 2018
The performance of the traditional second-order statistics based channel estimation methods degrade seriously in the presence of impulsive noises.In order to deal with this problem,a Weibull distribution function based variable step-size sign algorithm ...
Rui ZHANG   +3 more
doaj   +2 more sources

Simulation based sequential Monte Carlo methods for discretely observed Markov processes [PDF]

open access: yes, 2014
Parameter estimation for discretely observed Markov processes is a challenging problem. However, simulation of Markov processes is straightforward using the Gillespie algorithm.
Neal, Peter
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

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