Results 71 to 80 of about 173,639,131 (247)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Outage Detection for Distribution Networks Using Limited Number of Power Flow Measurements

Journal of Modern Power Systems and Clean Energy, 2020
Accurate topology estimation is crucial for effectively operating modern distribution networks. Line outages in a distribution network change the network topology by disconnecting some parts of the network from the main grid.
Basel Alnajjab, Ananth Narayan Samudrala, Chen Chen, Rick S. Blum, Soummya Kar, Emma M. Stewart   +5 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

A Novel Gaussian Particle Swarms optimized Particle Filter Algorithm for the State of Charge Estimation of Lithium-ion Batteries

International Journal of Electrochemical Science, 2020
A gaussian particle swarm optimized particle filter estimation method, along with the second-order resistance-capacitance model, is proposed for the state of charge estimation of lithium-ion battery in electric vehicles.
Xinyang Wang, Shunli Wang, Junhan Huang, Carlos Fernandez, Yicong Zhou, Lei Chen   +5 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Low-complexity variable step-size sign algorithm based on Weibull distribution function

Dianxin kexue, 2018
The performance of the traditional second-order statistics based channel estimation methods degrade seriously in the presence of impulsive noises.In order to deal with this problem,a Weibull distribution function based variable step-size sign algorithm ...
Rui ZHANG, Guchen SHI, Banteng LIU, Yourong CHEN   +3 more
doaj   +2 more sources

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

An augmented estimation of distribution algorithm for multi-carpooling problem with time window

, 2016
A multi-carpooling model is proposed for the multi-vehicle carpooling problem in a distributed parallel computing environment. A two-stage stochastic optimization of the estimation of distribution algorithm solves the optimum of the multi-carpooling ...
Kuang FJ(匡方军), Wang Y(汪扬), Zhang F(张芳), Yang ZJ(杨志家)   +3 more
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