Results 61 to 70 of about 1,087,874 (283)

The reliability assessment of the electromagnetic valve of high-speed electric multiple units braking system based on two-parameter exponential distribution

open access: yesAdvances in Mechanical Engineering, 2016
In order to solve the reliability assessment of braking system component of high-speed electric multiple units, this article, based on two-parameter exponential distribution, provides the maximum likelihood estimation and Bayes estimation under a type-I ...
Jianwei Yang   +4 more
doaj   +1 more source

Multi-Objective Deep Network-Based Estimation of Distribution Algorithm for Music Composition

open access: yesIEEE Access, 2022
In the field of evolutionary algorithm music composition, most of the current researches focus on how to enhance environmental selection based on multi-objective evolutionary algorithms (MOEAs).
Jae-Hun Jeong   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Average Time Complexity of Estimation of Distribution Algorithms

open access: yes, 2005
This paper presents a study based on the empirical results of the average first hitting time of Estimation of Distribution Algorithms. The algorithms are applied to one example of linear, pseudo-modular, and unimax functions. By means of this study, the paper also addresses recent issues in Estimation of Distribution Algorithms: (i) the relationship ...
González Morgado, Cristina   +3 more
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Smart Meter Measurement-Based State Estimation for Monitoring of Low-Voltage Distribution Grids

open access: yesEnergies, 2020
The installation of smart meters at customer premises provides opportunities for the monitoring of distribution grids. This paper addresses the problem of improving the observability of low-voltage distribution grids using smart metering infrastructure ...
Karthikeyan Nainar, Florin Iov
doaj   +1 more source

An estimation of distribution algorithm for nurse scheduling [PDF]

open access: yesAnnals of Operations Research, 2007
Schedules can be built in a similar way to a human scheduler by using a set of rules that involve domain knowledge. This paper presents an Estimation of Distribution Algorithm (eda) for the nurse scheduling problem, which involves choosing a suitable scheduling rule from a set for the assignment of each nurse.
Aickelin, U, Li, J
openaire   +7 more sources

Home - About - Disclaimer - Privacy