Results 91 to 100 of about 787,704 (278)

Side chain placement using estimation of distribution algorithms

Artificial Intelligence in Medicine, 2007
This paper presents an algorithm for the solution of the side chain placement problem.The algorithm combines the application of the Goldstein elimination criterion with the univariate marginal distribution algorithm (UMDA), which stochastically searches the space of possible solutions.
Santana Hermida, Roberto, Larrañaga Múgica, Pedro María, Lozano, José Antonio   +2 more
openaire   +3 more sources

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

PERMMA: Enhancing parameter estimation of software reliability growth models: A comparative analysis of metaheuristic optimization algorithms.

PLoS ONE
Software reliability growth models (SRGMs) are universally admitted and employed for reliability assessment. The process of software reliability analysis is separated into two components.
Vishal Pradhan, Arijit Patra, Ankush Jain, Garima Jain, Ajay Kumar, Joydip Dhar, Anjan Bandyopadhyay, Saurav Mallik, Naim Ahmad, Ahmed Said Badawy   +9 more
doaj   +1 more source

Interactions and Dependencies in Estimation of Distribution Algorithms

2005 IEEE Congress on Evolutionary Computation, 2005
In this paper, we investigate two issues related to probabilistic modeling in Estimation of Distribution Algorithms (EDAs). First, we analyze the effect of selection in the arousal of probability dependencies in EDAs for random functions. We show that, for these functions, independence relationships not represented by the function structure are likely ...
Santana Hermida, Roberto, Larrañaga Múgica, Pedro María, Lozano Alonso, José Antonio   +2 more
openaire   +2 more sources

Neuroinflammation in GAD65 Antibody‐Associated Epilepsy Measured Using [18F]DPA‐714 PET/MRI

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The timing for initiating immunotherapy in patients with glutamic acid decarboxylase 65 (GAD65) antibody‐associated epilepsy is a challenge. We used the translocator protein radioligand [18F]DPA‐714 and PET to evaluate brain microglial activation.
Jingjing Chen, Yuying Zhang, Heyu Zhang, Jinming Zhang, Ningning Wang, Xintong Guo, Yicong Liu, Yue Liu, Xiangsong Zhang, Ziyi Chen, Guanzhong Ni   +10 more
wiley   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

High-Performance Binocular Disparity Prediction Algorithm for Edge Computing

Sensors
End-to-end disparity estimation algorithms based on cost volume deployed in edge-end neural network accelerators have the problem of structural adaptation and need to ensure accuracy under the condition of adaptation operator.
Yuxi Cheng, Yang Song, Yi Liu, Hui Zhang, Feng Liu   +4 more
doaj   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Maximizing Nash Social Welfare Based on Greedy Algorithm and Estimation of Distribution Algorithm

Biomimetics
The Nash social welfare (NSW) problem is relevant not only to the economic domain but also extends its applicability to the field of computer science. However, maximizing Nash social welfare is an APX-hard problem.
Weizhi Liao, Youzhen Jin, Zijia Wang, Xue Wang, Xiaoyun Xia   +4 more
doaj   +1 more source

Exponentiated power Lindley distribution

Journal of Advanced Research, 2015
A new generalization of the Lindley distribution is recently proposed by Ghitany et al. [1], called as the power Lindley distribution. Another generalization of the Lindley distribution was introduced by Nadarajah et al.
Samir K. Ashour, Mahmoud A. Eltehiwy
doaj   +1 more source