Results 101 to 110 of about 1,932,383 (293)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Cost-Optimized Video Dissemination Over Heterogeneous Cloud With SLAs Support

open access: yesIEEE Access, 2019
A growing number of social video distribution services are turning toward to the cloud-based architecture for lower cost and better scalability. Although appealing, such a cloud content delivery network (cloud-based CDN) involves two key tasks: to ...
Zhiqiang Ruan, Xiucai Ye
doaj   +1 more source

Extreme Value Theory for Tail-Related Risk Measures [PDF]

open access: yes
Many fields of modern science and engineering have to deal with events which are rare but have significant consequences. Extreme value theory is considered to provide the basis for the statistical modeling of such extremes. The potential of extreme value
Evis Këllezi, Manfred Gilli
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Frontier Estimation and Extreme Values Theory [PDF]

open access: yes
In this paper we investigate the problem of nonparametric monotone frontier estimation from an extreme-values theory perspective. This allows to revisit the asymptotic theory of the popular Free Disposal Hull estimator in a general setup, to derive new ...
Daouia, Abdelaati   +2 more
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Multidimensional Polynomial Phase Estimation

open access: yesIEEE Open Journal of Signal Processing
An estimation method is presented for polynomial phase signals, i.e., those adopting the form of a complex exponential whose phase is polynomial in its indices. Transcending the scope of existing techniques, the proposed estimator can handle an arbitrary
Heedong Do, Namyoon Lee, Angel Lozano
doaj   +1 more source

Multi-radar target parameter estimation and fusion based on attribute scattering centre model

open access: yesThe Journal of Engineering, 2019
This study proposes a method of observing the same target from different radars to extract more useful target information, solving the problem of target occlusion in monostatic radar.
Chang Liu   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Quantifying insect migration across Bohai strait using weather radar

open access: yesThe Journal of Engineering, 2019
Weather radars provide continuous recording over extensive spatial coverage, which is valuable for biologists who observe and study biological activities over a wide range of temporal and spatial scales.
Kai Cui   +5 more
doaj   +1 more source

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