Results 91 to 100 of about 693,040 (378)
FEBS Letters, EarlyView.α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley +1 more source
Assessing Coupling Dynamics from an Ensemble of Time Series
Entropy, 2015 Finding interdependency relations between time series provides valuable knowledge about the processes that generated the signals. Information theory sets a natural framework for important classes of statistical dependencies.
Germán Gómez-Herrero +5 more
doaj +1 more source
Best Widely Linear Unbiased Estimator for Real Valued Parameter Vectors [PDF]
arXiv, 2016 For classical estimation with an underlying linear model the best linear unbiased estimator (BLUE) is usually utilized for estimating the deterministic but unknown parameter vector. In the case of real valued parameter vectors but complex valued measurement matrices and noise vectors, the BLUE results in complex valued estimates, introducing a ...
arxiv
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Double Reweighted Estimators for the Parameters of the Multivariate t Distribution [PDF]
arXiv, 2017 The t-distribution has many useful applications in robust statistical analysis. The parameter estimation of the t-distribution is carried out using ML estimation method, and the ML estimates are obtained via the EM algorithm. In this study, we consider an alternative estimation method for all the parameters of the multivariate-t distribution using the ...
arxiv
, 2004 The nonlinear fixed-effects model has two shortcomings, one practical and one methodological. The practical obstacle relates to the difficulty of computing the MLE of the coefficients of non-linear models with possibly thousands of dummy variable ...
W. Greene
semanticscholar +1 more source
Attitude Estimation or Quaternion Estimation? [PDF]
The Journal of the Astronautical Sciences, 2004 The absence of a globally nonsingular three-parameter representation of the rotation group forces attitude Kalman filters to estimate either a singular or a redundant attitude representation. We compare two filtering strategies using simplified kinematics and measurement models.
openaire +2 more sources
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Application of the Scaling Functions to Nonparametric Regression [PDF]
Informatică economică, 2007 For estimating regression function we can use many proceedings. In this paper, we have chosen to apply scaling functions to the estimation of regression functions.
doaj