Results 171 to 180 of about 309,036 (359)

In Vitro and Clinical Evaluations of UGT1A1‐, P‐gp‐, OATP1B1‐, and BCRP‐Mediated Drug–Drug Interactions of Belumosudil, a Potent ROCK2 Inhibitor

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Belumosudil is an oral selective rho‐associated coiled‐coil containing protein kinase 2 inhibitor, approved as a treatment for chronic graft‐versus‐host disease. Prior clinical studies demonstrated that coadministration with strong CYP3A4 inducers or proton pump inhibitors requires dose modification of belumosudil.
Olivier Schueller   +4 more
wiley   +1 more source

Removal of endocrine disrupting chemicals using low pressure reverse osmosis membrane [PDF]

open access: yes, 2009
Endocrine disrupting chemicals (EDCs) are one of the major focuses of contaminants in current environmental issues, as they can cause adverse health effects on animals and human, particularly to endocrine function.
Abd. Razak, Azri Rasyidi
core  

Trends in resource utilization for new‐onset psychosis hospitalizations at children's hospitals

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Background Children with new‐onset psychosis often require hospitalization for medical evaluation. Objectives The goal of this study was to assess variations in the management of children with new‐onset psychosis and characterize trends in resource utilization.
Ankita Gupta   +8 more
wiley   +1 more source

Effects of Incubation and Rearing Temperatures on Caiman latirostris Growth [PDF]

open access: yes, 2010
Different studies found that incubation temperature has an influence on the size of Caiman latirostris hatchlings and determines their gonadal sex. Experimental manipulations revealed that the effects of temperature on growth are independent of sex ...
Larriera, Alejandro   +3 more
core  

Establishment of a Predictive Model for the Efficacy of High‐Intensity Focused Ultrasound in the Treatment of Uterine Fibroids

open access: yesJournal of Ultrasound in Medicine, EarlyView.
Objectives High‐intensity focused ultrasound (HIFU) has demonstrated efficacy as a non‐invasive treatment for uterine fibroids, though individual variability exists. This study aims to develop a risk scoring model using clinical and biochemical features to predict HIFU treatment outcomes.
Huiqing Li   +6 more
wiley   +1 more source

Effect of Estradiol valerate on pancreatic beta cells resistance in diabetic female rats by streptozotocin

open access: yesIranian South Medical Journal, 2014
Background: Diabetes mellitus (DM) is the most common metabolic disorder, with defective insulin secretion or insulin receptor function, or both. We examined the protective effect of estradiol against the destruction of pancreatic β-cells by ...
Zabihollah Azizi   +4 more
doaj  

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