DNA methylome changes by estradiol benzoate and bisphenol A links early-life environmental exposures to prostate cancer risk. [PDF]
Developmental exposure to endocrine-disrupting chemicals (EDCs), 17β-estradiol-3-benzoate (EB) and bisphenol A (BPA), increases susceptibility to prostate cancer (PCa) in rodent models.
Cheong A+9 more
europepmc +4 more sources
Vitamin B12 and estradiol benzoate improve memory retrieval through activation of the hippocampal AKT, BDNF, and CREB proteins in a rat model of multiple sclerosis [PDF]
Objective(s): Multiple sclerosis (MS) causes extensive damage in the hippocampus. Vitamin B12 (vit B12) and estradiol benzoate (EB) have anti-inflammatory and re-myelination properties that make them proper in improvement of cognitive impairment.
Narjes Taherian+5 more
doaj +2 more sources
Progesterone-based fixed-time artificial insemination protocols for dairy cows: Gonadotropin-releasing hormone versus estradiol benzoate at initiation and estradiol cypionate versus estradiol benzoate at the end [PDF]
Our objectives were to evaluate ovarian dynamics and fertility comparing 2 treatments at the start of a progesterone (P4)-based fixed-time artificial insemination (FTAI) protocol and 2 treatments at the end of the protocol. Thus, 1,035 lactating Holstein cows were assigned in a random phase of the estrous cycle to 1 of 4 treatments using a completely ...
J. N. Drum+5 more
openaire +4 more sources
Reproductive biotechnologies emerge as an important element for livestock, however, some strategies must be modified to adapt the different breeding systems, such as the use of follicular synchronization protocols.
Maria Fernanda Zamai+7 more
doaj +3 more sources
Protective Effects of Irbesartan, an Angiotensin Receptor Blocker with PPARγ Agonistic Activity, against Estradiol Benzoate-Induced Endometrial Hyperplasia and Atypia in Female Rats via Modulation of TNFα/Survivin Pathway [PDF]
Endometrial hyperplasia (EH) is a common gynecological problem and may progress to carcinoma. Early detection and management of EH are mandatory for the prevention of endometrial cancer.
Mohamed A. Morsy+3 more
doaj +2 more sources
Estradiol benzoate Description Estradiol analog which binds to the human, murine and chicken ERα with IC50 of 22-28 nM. Biological description Estradiol analog which contains a benzyl ester at the C-3 position.
openaire +2 more sources
Identification of potential VP40 inhibitor of Marburg virus through molecular docking, pharmacokinetic analysis and molecular dynamics simulation [PDF]
West Africa has been experiencing a resurgence of Marburg virus disease (MVD), a zoonotic pathogen that causes severe hemorrhagic fever in both humans and primates. Regretfully, there are not any effective medications on the market right now. The binding
Rohit Das+3 more
doaj +2 more sources
Integrative genomic and bioinformatic prioritization of drug repurposing candidates for prostate cancer [PDF]
Objective Prostate cancer remains a prevalent global health challenge, with limited treatment options for advanced stages. There is a critical need to identify effective therapies through systematic integration of genomic and biological data.
Lalu Muhammad Irham+12 more
doaj +2 more sources
Efficacy of Short-Term Timed Artificial Insemination Protocols With Estradiol Esters and PGF2α in Girolando Cows. [PDF]
ABSTRACT Using a synchronisation protocol based on estradiol esters and prostaglandin, established in cattle since the 1970s, we implemented 24 or 48‐h intervals between hormone administration and timed artificial insemination (TAI). This study compared two short‐duration TAI protocols using estradiol benzoate (EB) and cypionate (EC) as ovulation ...
Dos Santos Dutra Okada M+4 more
europepmc +2 more sources
Detectability of testosterone esters and estradiol benzoate in bovine hair and plasma following pour-on treatment [PDF]
The abuse of synthetic esters of natural steroids such as testosterone and estradiol in cattle fattening and sports is hard to detect via routine urine testing. The esters are rapidly hydrolysed in vivo into substances which are also endogenously present
A. Stolker+8 more
semanticscholar +2 more sources