Diacerein inhibits Estradiol-benzoate induced cervical hyperkeratosis in female rats
Biomedicine & Pharmacotherapy, 2017 Cervical hyperkeratosis is a common gynecological lesion and usually caused by inflammation or trauma. We investigated the effect of Diacerein on Estradiol benzoate-induced cervical hyperkeratosis. Diacerein (50mg/kg/day) was given orally to rats for 4 weeks in the presence or absence of cervical hyperkeratosis induced by intramuscular injection of ...
Marwa M M, Refaie, Maram, El-Hussieny
semanticscholar +5 more sources
Vitamin B12 and estradiol benzoate improve memory retrieval through activation of the hippocampal AKT, BDNF, and CREB proteins in a rat model of multiple sclerosis [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): Multiple sclerosis (MS) causes extensive damage in the hippocampus. Vitamin B12 (vit B12) and estradiol benzoate (EB) have anti-inflammatory and re-myelination properties that make them proper in improvement of cognitive impairment.
Narjes Taherian +5 more
doaj +2 more sources
Plasma Estradiol and Endometrial Edema Profile in Acyclic Mares After Single Administration of 17-β Estradiol, Estradiol Benzoate and Estradiol Cypionate. [PDF]
Reprod Domest AnimABSTRACTA longer endometrial exposure to estradiol before progesterone has been shown to be beneficial in cyclic and acyclic recipient mares. Therefore, the selection of an estradiol ester that promotes longer endometrial exposure to estradiol using a single administration would be advantageous when preparing acyclic mares as embryo recipients.
Barbosa LA +7 more
europepmc +2 more sources
Identification of potential VP40 inhibitor of Marburg virus through molecular docking, pharmacokinetic analysis and molecular dynamics simulation [PDF]
Scientific ReportsWest Africa has been experiencing a resurgence of Marburg virus disease (MVD), a zoonotic pathogen that causes severe hemorrhagic fever in both humans and primates. Regretfully, there are not any effective medications on the market right now. The binding
Rohit Das +3 more
doaj +2 more sources
Alterations in liver enzymes and histopathological changes in an animal model of polycystic ovary syndrome [PDF]
Open Veterinary JournalBackground: Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder that can lead to metabolic and reproductive complications, including liver dysfunction.
Yudit Oktanella +6 more
doaj +2 more sources
Estradiol benzoate treatment before ovum pick-up increases the number of good quality oocytes retrieved and improves the production of transferable embryos in Japanese Black cattle [PDF]
Veterinary and Animal Science, 2018 The aim of this study was to evaluate the efficacy of treatment with estradiol benzoate (EB) at luteal phase prior to the ovum pick-up (OPU) during in vitro production of transferable embryos in Japanese Black cattle.
Takemasa Hidaka +4 more
doaj +2 more sources
Integrative genomic and bioinformatic prioritization of drug repurposing candidates for prostate cancer [PDF]
BMC Pharmacology and ToxicologyObjective Prostate cancer remains a prevalent global health challenge, with limited treatment options for advanced stages. There is a critical need to identify effective therapies through systematic integration of genomic and biological data.
Lalu Muhammad Irham +12 more
doaj +2 more sources
Effects of timed artificial insemination following estrus synchronization in postpartum beef cattle [PDF]
Open Veterinary Journal, 2012 The objectives of this study were to evaluate estrus response and pregnancy rates resulting from timed artificial insemination (AI) following estrus synchronization using CIDR in postpartum beef cattle.
M. Sabri +4 more
doaj +3 more sources
Fundamental and Clinical Pharmacology, 2017 M. Refaie, M. El-hussieny
semanticscholar +3 more sources