Results 111 to 120 of about 12,682 (158)

Luminescent Biological Probes Derived from Ruthenium(II) Estradiol Polypyridine Complexes

Inorganic Chemistry, 2007
Four luminescent ruthenium(II) polypyridine estradiol complexes [Ru(NwedgeN)2(bpy-estradiol)](PF6)2 (NwedgeN = 2,2'-bipyridine (bpy), 4,7-diphenyl-1,10-phenanthroline (Ph2-phen); bpy-estradiol = 5-(4-(17alpha-ethynylestradiolyl)phenyl)-2,2'-bipyridine (bpy-ph-est), 4-(N-(6-(4-(17alpha-ethynylestradiolyl)benzoylamino)hexyl)aminomethyl)-4'-methyl-2,2 ...
Kenneth Kam-Wing, Lo, Terence Kwok-Ming, Lee, Jason Shing-Yip, Lau, Wing-Lin, Poon, Shuk-Han, Cheng   +4 more
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Synthesis and Estrogenic Activity Screening of Some 6,9-Disubstituted Estradiol Derivatives

Collection of Czechoslovak Chemical Communications, 2005
Oxidation of estradiol dipropionate (1) with chromium(VI) oxide-3,5-dimethylpyrazole complex yielded 9α-hydroxy-6-oxoestra-1,3,5(10)-triene-3,17β-diyl dipropionate (2) and 6-oxoestra-1,3,5(10)-triene-3,17β-diyl dipropionate (3). Dehydration of compound 2 with phosphorus(V) oxide or acetic anhydride gave 6-oxoestra-1,3,5(10),9(11)-tetraene-3,17β-diyl ...
Sakač, Marija, Penov-Gaši, Katarina, Popsavin, Mirjana, Đurendić, Evgenija, Andrić, Silvana, Kovačević, Radmila   +5 more
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Synthesis and biological activity of 17α-alkynylamide derivatives of estradiol

The Journal of Steroid Biochemistry and Molecular Biology, 1991
Seven estradiol (E2) derivatives with an alkynylamide side chain at the 17 alpha position were synthesized starting from ethynylestradiol (EE2). The main chemical step was the coupling reaction of the acetylide ion of EE2 with carbon dioxide, glutaric anhydride or bromoalkyl ortho ester.
D, Poirier, C, Labrie, Y, Mérand, F, Labrie   +3 more
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Chromatographic Behaviour and Lipophilicity of Estradiol Derivatives

Chromatographia, 2005
The retention behaviour of estradiol derivatives has been studied by HPLC on polar chemically bonded stationary phases: C3CN, DIOL and C3NH2, commercially available columns. The mobile phases used were: methanol-water and acetonitrile-water in various proportions.
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Some ring a methoxy-derivatives of estrone and estradiol-17β

Steroids, 1967
Abstract The synthesis of 1,2,3-trimethoxyestra-1,3,5(10)-trien-17β-ol (II) and 1,3,4-trimethoxyestra-1,3,5(10)-trien-17β-ol (III), and related compounds is described.
R B, Conrow, E W, Cantrall, S, Bernstein
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Estramicins: a novel cyclic diyl precursor derived from estradiol

Tetrahedron Letters, 1997
Abstract The estradiol derived ynone 2 is obtained via a 13 step sequence starting from estrone. One of the key-steps involves the addition to estrone derivative 3 of the lithio derivative 8. Obtention of the latter in enantiomerically pure form involves the lipase mediated kinetic resolution of racemic alcohol (±) 5.
Christel Meert, Jing Wang, Pierre J. De Clercq   +2 more
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SYNTHESIS OF 17α-SUBSTITUTED MERCAPTOALKYNYL DERIVATIVES OF 3,17β-ESTRADIOL

Tetrahedron Letters, 1997
Abstract A homologous series of 17α-substituted mercaptoalkynyl estradiols have been prepared by addition of lithium acetylides to TBDMS-protected estrone © 1997 Published by Elsevier Science Ltd.
Frank Wüst, Hartmut Spies, Bernd Johannsen   +2 more
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Estramycins: a potential acyclic diyl precursor derived from estradiol

Tetrahedron Letters, 1996
The estradiol derived enyne 2 is obtained via a nine step sequence starting from estrone. Key-steps involve the opening of the α-epoxide 7 and the 1,2-addition of propargylmagnesium bromide on the allene ketone 10. The allylic alcohol 2 possesses the required functionalities for yielding, after dehydratation, the unsaturated core structure that is ...
Wang Jing, Pierre J. De Clercq
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ChemInform Abstract: Syntheses and Properties of Fluorescent Estradiol Derivatives.

Chemischer Informationsdienst, 1986
AbstractDie Synthese und Fluoreszenzeigenschaften der Östradiol‐Derivate (III) und (VI) werden beschrieben.
B. + MUEHLENBRUCH, F. KIRMEIER, H. J. ROTH   +2 more
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Inhibition of 5α-reductase activity of rat prostate by estradiol derivatives

Biochimie, 1973
Summary The in vitro inhibitory effect of estradiol and of three of its estrogenic and non-estrogenic derivatives on 5α-reductase activity in rat prostate microsomes is studied. The results establish that this effect is not correlated with their uterotrophic activity, nor with their in vitro affinity for the uterus cytosol estrogen receptor.
C, Bonne, J P, Raynaud
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