Results 91 to 100 of about 744,343 (249)

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

Structural and dynamic characterization of estrogen receptor-α binding by bisphenol A and its analogues

Discover Chemistry
Bisphenol A (BPA) and related chemicals are widely present in the environment and can interact with hormone receptors in the body. The estrogen receptor alpha (ERα) is considered a key target of these endocrine-disrupting compounds.
Raghunath Satpathy
doaj   +1 more source

Mesyl chloride-mediated synthesis and in vitro anticancer evaluation of 2-carboxamide derivatives of estrone and estradiol

Results in Chemistry
The 2-carboxamide derivatives of estrone (E1) and estradiol (E2) offer untapped anticancer potential, mimicking active 2-methoxyestradiol (2ME2). We synthesized a 12-member library via a mesyl chloride (MsCl)-mediated protocol that overcame steric ...
András Novák, Barnabás Molnár, Ildikó Huliák, Hédi Árva, Eszter Nagy, Zoltán Kele, Mónika Kiricsi, Éva Frank   +7 more
doaj   +1 more source

Coincidence of Persistent Müllerian duct syndrome and testicular tumors in dogs

BMC Veterinary Research, 2017
Background Persistent Müllerian duct syndrome (PMDS), a rare form of male pseudohermaphroditism in dogs, is an abnormal sexual phenotype in males that is characterized by the existence of a hypoplastic oviduct, uterus, and cranial part of the vagina ...
Eun Jung Park, Seok-Hee Lee, Young-Kwang Jo, Sang-Eun Hahn, Do-Min Go, Su-Hyung Lee, Byeong-Chun Lee, Goo Jang   +7 more
doaj   +1 more source

Korelasi Kadar Estradiol dan Kadar Leptin dengan Profil Lipid pada Wanita Obesitas, Overweight dan Berat Badan Normal di Kota Banda Aceh

, 2015
Background: The prevalence of obesity at woman was higher than man. Obesity related to leptin resistance that causes hipertrigliseridemia that known as an overview of lipid metabolism disorders.
Fitri, Yulia
core  

A Specific Association between Facial Disgust Recognition and Estradiol Levels in Naturally Cycling Women. [PDF]

, 2015
Subtle changes in social cognition are associated with naturalistic fluctuations in estrogens and progesterone over the course of the menstrual cycle.
H. Valerie Curran (724366), Sunjeev K. Kamboj (724364), H Valerie Curran, Kathleen M. Krol (724365), Curran, H., Kathleen M Krol, Curran H. Valerie, Krol, KM, Curran, HV, Krol, K., Kamboj Sunjeev K., Kamboj, SK, Kamboj, S., Krol Kathleen M., Sunjeev K Kamboj   +14 more
core   +2 more sources

Systemic menopausal hormone therapy treatment patterns in Danish women—A nationwide drug utilization study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Objectives This paper aims to describe the treatment patterns of contemporary systemic menopausal hormone therapy (MHT) in Denmark. Study design This study is a nationwide drug utilization study including an open cohort of all Danish women aged >40 years between 2000–2024.
Hannah K. Wood‐Kurland, Kathrine Kold Sørensen, Amalie Lykkemark Møller, Lina Steinrud Mørch, Mikkel Porsborg Andersen, Thomas Alexander Gerds, Amani Meaidi, Christian Torp‐Pedersen   +7 more
wiley   +1 more source

Effects of micronized progesterone added to non-oral estradiol on lipids and cardiovascular risk factors in early postmenopause: a clinical trial

Lipids in Health and Disease, 2012
Background Much attention has been drawn to the deleterious effects of adding progestins to estrogen as hormone therapy (HT) in postmenopausal women.
Casanova Gislaine, Spritzer Poli
doaj   +1 more source

Research Progress on V2CTx MXene‐Based Composites: Synthetic Strategies, Structure Design, and Multifunctional Applications

Carbon Energy, EarlyView.
This review systematically and comprehensively summarizes the latest research progress on V2CTx MXene. Focusing on the structural design strategies, particularly the construction of the V2CTx‐based hetero‐composite structure. Furthermore, widespread applications including electrochemical energy storage and conversion, as well as photocatalytic ...
Wenjun Zhu, Minghai Zhao, Min Fan, Jianmin Luo, Jian Tian, Xinhui Xia, Wenkui Zhang, Xinyong Tao, Yanxian Jin, Yang Xia   +9 more
wiley   +1 more source

Clinical Pharmacology in Transgender Medicine: What Gaps Remain?

Clinical Pharmacology &Therapeutics, EarlyView.
Mechanistic information is limited about the effects of gender‐affirming hormone therapy and the unique factors that influence the absorption, distribution, metabolism, and excretion properties of medications across therapeutic classes for transgender people.
Lauren R. Cirrincione
wiley   +1 more source