Results 101 to 110 of about 709,941 (344)

Matrix Tropism Influences Endometriotic Cell Attachment Patterns

Advanced Functional Materials, EarlyView.
The influence of substrate stiffness and multicellular coculture on endometriotic cell attachment to extracellular matrix‐laden microarrayed islands is reported. This model investigates early endometriotic cell attachment, aiming to capture “lesion initiation events”.
Hannah S. Theriault, Hannah R.C. Kimmel, Alison C. Nunes, Allison L. Paxhia, Sarah Hashim, Kathryn B.H. Clancy, Gregory H. Underhill, Brendan A.C. Harley   +7 more
wiley   +1 more source

Estrogenic Effect of 70% Ethanol Turmeric (Curcuma domestica Val.) Extract on Ovariectomized Female Mice (Mus musculus L.)

Makara Seri Sains, 2007
The influence of extract turmeric (Curcuma domestica Val.) on endometrium thickness, vaginal epithelium, mammary gland, and protein of estrogen receptor of ovariectomized mice was examined.
A.N. Dewi, P.R. Ratri, R.R.R. Soraya, Dadang Kusmana, R. Lestari   +4 more
doaj  

Chronic effect of antidopaminergic drugs or estrogen on male Wistar rat lactotrophs and somatotrophs

Brazilian Journal of Medical and Biological Research, 1999
The aim of the present study was to evaluate the effect of antidopaminergic agents on the somatotrophs in the presence of hyperprolactinemia. Adult male Wistar rats were divided into 6 groups: a control group and five groups chronically treated (60 days)
M.C. Oliveira, H.P. Messinger, M. Tannhauser, L. Barbosa-Coutinho   +3 more
doaj   +1 more source

Hypoxia Upregulates Estrogen Receptor β in Pulmonary Artery Endothelial Cells in a HIF-1α-Dependent Manner [PDF]

, 2018
17β-Estradiol (E2) attenuates hypoxia-induced pulmonary hypertension (HPH) through estrogen receptor (ER)-dependent effects, including inhibition of hypoxia-induced endothelial cell proliferation; however, the mechanisms responsible for this remain ...
Albrecht, Marjorie, Frump, Andrea L., Lahm, Tim, Petrache, Irina, Selej, Mona, Wood, Jordan A., Yakubov, Bakhtiyor   +6 more
core   +1 more source

Metal Nanoclusters for Cancer Imaging and Treatment

Advanced Functional Materials, EarlyView.
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu, Ziping Wang, Qiaofeng Yao, Ping Zhang, Jianping Xie, Xun Yuan   +5 more
wiley   +1 more source

Estrogen-dependent dynamic profile of eNOS-DNA associations in prostate cancer [PDF]

, 2013
In previous work we have documented the nuclear translocation of endothelial NOS (eNOS) and its participation in combinatorial complexes with Estrogen Receptor Beta (ERβ) and Hypoxia Inducible Factors (HIFs) that determine localized chromatin remodeling ...
A Grasselli, A Re, A Watahiki, Agnese Re, Alessandro Guffanti, Alfredo Pontecorvi, Antonella Farsetti, Armando Felsani, Arturo Londono-Vallejo, Aurora Aiello, BD Gehm, C Liu, C Zang, Carlo Gaetano, Claudia Colussi, Costanza Emanueli, CS Ross-Innes, D Bonci, D Fukumura, D Lodygin, DM Huffman, E Schreiber, G Garcia-Cardena, I Mattagajasingh, J Lu, J Veldscholte, JA Baur, JS Carroll, JS Horoszewicz, KH Lim, KP Porkka, L Ying, L Zeng, LJ Zhu, Luis Jaime Castro-Vega, M Yamakuchi, M Yamakuchi, Maurizio C. Capogrossi, MC Haigis, MD Kornberg, MD Robinson, ME Ritchie, MS Zaman, MV Iorio, N Hah, N Nadiminty, NR Bertos, OM Grober, P Gandellini, P Giovannelli, Q Wu, RT Prehn, S Anders, S Baranwal, S Kyo, S Misiti, S Nanni, S Nanni, S Nanni, S Volinia, Silvia Bacchetti, Simona Nanni, T Liu, T Vanhaecke, Valentina Benvenuti, W Fischle, Y Zhang   +66 more
core   +3 more sources

Antibody‐Programmable Bimetallic Nanozymes for Transcriptional Blockade Therapy in HER2/ER‐Positive Breast Cancer

Advanced Functional Materials, EarlyView.
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao, Tong Ye, Mingjiang Liu, Jingchao Gao, Lian Tan, Qian Dong, Qingbo Lv, Qianqian Ye, Yu Wang   +8 more
wiley   +1 more source

Design and Synthesis of Novel Breast Cancer Therapeutic Drug Candidates Based upon the Hydrophobic Feedback Approach of Antiestrogens

Molecules, 2019
Based upon hydrophobic feedback approaches, we designed and synthesized novel sulfur-containing ERα modulators (4 and 5) as breast cancer therapeutic drug candidates. The tetrahydrothiepine derivative 5a showed the highest binding affinity toward ER&
Kiminori Ohta, Asako Kaise, Fumi Taguchi, Sayaka Aoto, Takumi Ogawa, Yasuyuki Endo   +5 more
doaj   +1 more source

Bazedoxifene, a selective estrogen receptor modulator, reduces cerebral aneurysm rupture in Ovariectomized rats. [PDF]

, 2017
BackgroundEstrogen deficiency is thought to be responsible for the higher frequency of aneurysmal subarachnoid hemorrhage in post- than premenopausal women.
Hashimoto, Tomoki, Kitazato, Keiko T, Korai, Masaaki, Maekawa, Hidetsugu, Miyamoto, Takeshi, Nagahiro, Shinji, Satomi, Junichiro, Tada, Yoshiteru, Yagi, Kenji   +8 more
core   +1 more source

Integration of Bioengineered Tools in Assisted Reproductive Technologies

Advanced Healthcare Materials, EarlyView.
A conceptual illustration depicting the collaboration between a medical professional (right) and a scientist (left). Their connection highlights the integration of scientific research and clinical practice. This representation underscores the role of emerging technologies in bridging fundamental research with applied reproductive healthcare.
Aslı Ak, Edith Coonen, Ron van Golde, Erik Vrij   +3 more
wiley   +1 more source