Results 81 to 90 of about 430,922 (218)

Estrogen Receptor Beta in Cancer: an Attractive Target for Therapy

, 2012
While it is well documented that the mitogenic actions of estrogens are critical in the development and progression of human breast and some gynecologic cancers, only latest data demonstrate a crucial involvement of estrogen-signaling in the ...
Scambia, Giovanni, Ferrandina, Maria Gabriella, Gallo, Daniela, De Stefano, Ilaria   +3 more
core   +1 more source

Sex differences and the role of estrogens in the immunological underpinnings of Alzheimer's disease

Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Alzheimer's disease (AD) affects women more frequently and more severely than men, but the biological mechanisms underlying these sex differences remain poorly understood.
Brittani R. Price, Keenan A. Walker, Jaclyn M. Eissman, Vidyani Suryadevara, Lindsey N. Sime, Timothy J. Hohman, Marcia N. Gordon   +6 more
doaj   +1 more source

Epilepsy and Sex Hormones

Archives of Epilepsy, 2018
There is a mutual interaction between sex steroid hormones and epilepsy. Although female and male sex hormones and their metabolites access the brain via the blood brain barrier, they can also be synthesized de novo from cholesterol within the glia and ...
Emine GENÇ, Bülent Oğuz GENÇ
doaj   +1 more source

Quantitative molecular assay for fingerprinting microbial communities of wastewater and estrogen-degrading consortia

, 2005
A quantitative fingerprinting method, called the real-time terminal restriction fragment length polymor-phism (real-time-t-RFLP) assay, was developed for simultaneous determination of microbial diversity and abundance within a complex community. The real-
Estrogen-degrading Consortia
core  

The impact of hormone replacement therapy on cardiovascular health in postmenopausal women: a narrative review

Frontiers in Reproductive Health
Menopause represents a pivotal transition in women's health, characterized by loss of ovarian hormone production and substantially increased cardiovascular disease (CVD) risk.
Hafsah Tajammul Khalifey, Rutaba Mahereen, Raghda Adwan, Rafah Chahine, Marwa Kaidali, Samra Farhat Mirza, Sarah Noor Tullah, Saniyah Shaikh, Shahad Hammad, Hatouf H. Sukkarieh   +9 more
doaj   +1 more source

Estrogen-Initiated Transformation of Prostate Epithelium Derived from Normal Human Prostate Stem-Progenitor Cells

, 2011
The present study sought to determine whether estrogens with testosterone support are sufficient to transform the normal human prostate epithelium and promote progression to invasive adenocarcinoma using a novel chimeric prostate model.
Dan-Ping Hu (7926677), Wen-Yang Hu, Shuk-Mei Ho, Shuk-Mei Ho (128463), Gail S. Prins (7926581), Ikenna C. Madueke, Hung-Ming Lam, Andre Kajdacsy-Balla, Andre Kajdacsy-Balla (2861), Ikenna C. Madueke (7926680), Guang-Bin Shi (7926674), Dan-Ping Hu, Wen-Yang Hu (479587), Guang-Bin Shi, Gail S. Prins, Hung-Ming Lam (758102)   +15 more
core   +1 more source

Effects of estradiol, tamoxifen, and raloxifene on human temporal lobe cortex astroglial cell spreading

Gynecological Endocrinology
Background Astrocytes, once regarded as passive support cells, are recognized as active regulators of synaptic organization and neuronal integration.
Ivaldo Silva, Frederick Nicholas Naftolin, Vinicius Oliveira Santana, Anne Williamson, Ahmed Fadiel, Dennis Spencer, Howard J. Li   +6 more
doaj   +1 more source

3D model of amphioxus steroid receptor complexed with estradiol

, 2009
The origins of signaling by vertebrate steroids are not fully understood. An important advance was the report that an estrogen-binding steroid receptor [SR] is present in amphioxus, a basal chordate with a similar body plan as vertebrates.
Michael E. Baker, David J. Chang
core  

Estrogen receptor co-regulators as prognostic and predictive markers of endocrine therapy in early breast cancer: the role of SMRT and p160 family

, 2010
Background: The estrogen receptor (ER) signaling pathway is the dominant driver of cell proliferation and survival in the majority of human breast cancers.
Migliaccio, Ilenia
core  

Detection of mRNA levels for the estrogen alpha, estrogen beta and androgen nuclear receptor genes in archival breast cancer tissue

, 2006
Previous studies in our laboratory have shown association of nuclear receptor expression and histological breast cancer grade. To further investigate these findings, it was the objective of this study to determine if expression levels of the estrogen ...
Weinstein, Stephen, Lea, Rodney, Griffiths, Lyn R., Smith, Robert, Griffiths, Lyn, Lea, Rod A., Smith, Robert A., Weinstein, Stephen R.   +7 more
core   +1 more source