Results 101 to 110 of about 484,589 (309)

Estrogen-responsive genes in the parenchyma and fat pad of the bovine mammary gland by microarray analysis

, 2006
Characterizing estrogen-responsive genes is an essential step towards fully understanding mechanisms of estrogen action during mammary gland development and function.
Bovine Functional Genomics Laboratory, Animal & Natural Resources Institute, USDA (17855084)
core  

Sex dimorphisms in the neuroprotective effects of estrogen in an animal model of Parkinson's disease

, 2004
The incidence of certain neurological disorders, including Parkinson's disease, appears to be more prevalent in men. Studies involving estrogen treatment of ovariectomised rodents attribute this largely to the neuroprotective effects of estrogen. However,
Gillies, G.E., McArthur, S., Murray, H.E., Dexter, D.T.   +3 more
core   +1 more source

Immunomodulation by estrogen and estren [PDF]

, 2007
Estrogen affects the development and regulation of the immune system. Treatment of gonadectomized mice with estrogen results in suppression of T and B lymphopoiesis, as well as decreased delayed type hypersensitivity reaction, granulocyte mediated ...
Islander, Ulrika
core   +1 more source

Multi‐Omics Integration Identifies a CDH3‐Associated Malignant Epithelial State and Immunosuppressive Niche to Predict Prognosis in Thymic Epithelial Tumors

Advanced Science, EarlyView.
Single‐cell, spatial, molecular, and pathology analyses identify a CDH3‐associated malignant epithelial state in thymic epithelial tumors. This state links stem‐like and EMT programs to M2 macrophage–rich immunosuppressive niches, genomic instability, poor survival, and drug vulnerability.
Yuntao Feng, Jingyu Chen, Lang Xia, Tao Wang, Yuzhou Wang, Lei Zhang, Guofang Zhao, Long Xu, Juemin Yu, Yunlang She, Junqi Wu, Yue Zhao, Chang Chen, Deping Zhao   +13 more
wiley   +1 more source

Analysis of high-dose tamoxifen therapy efficiency in complex treatment of patients with stage III-IV non-small cell lung cancer

Zaporožskij Medicinskij Žurnal, 2012
With the help of immunohistochemcial methods the frequency of estrogen and progesteron expression in tumor tissue of 30 patients with non-small cell lung cancer was analysed, positive result took place in 1 patient (3%). Assessment of effi ciency of high
A. I. Shevchenko, A. V. Kadzhoyan
doaj   +1 more source

Anterior prostate epithelial AR inactivation modifies estrogen receptor expression and increases estrogen sensitivity

, 2011
*This article is free to read on the publisher's website* \ud \ud Androgens influence prostate growth and development, so androgen withdrawal can control progression of prostate diseases. Although estrogen treatment was originally used to induce androgen
Handelsman, David, McNamara, Keely, Jimenez, Mark, Desai, Reena, Ulla Simanainen, David J. Handelsman, Simanainen, Ulla, Mark Jimenez, Gao, Yan Ru, McPherson, Stephen, Keely McNamara, Stephen McPherson, Yan Ru Gao, Reena Desai   +13 more
core   +1 more source

WTAP Transcriptional Suppression by KLF9 Drives Osteoclastogenesis via M6A‐Mediated Regulation of CSF1R Signaling in Estrogen‐Deficient Osteoporosis

Advanced Science, EarlyView.
Scheme of the KLF9/WTAP/YTHDF2/m6A/CSF1R regulatory axis in osteoclastogenesis and estrogen‐deficient osteoporosis. WTAP‐mediated m6A modification of Csf1r mRNA governs osteoclastogenesis via a YTHDF2‐mediated pathway. Pathological upregulation of KLF9 drives Wtap transcription, leading to increased m6A deposition on the 3’‐UTR of Csf1r mRNA.
Chen Shen, Xin Liu, Gaoran Ge, Li Xu, Ziyu Zhang, Chang Lv, Hao Xu, Wenhao Li, Yi Qin, Qifeng Sheng, Qihan Wang, Hongxia Li, Jun Zhou, Huilin Yang, Dechun Geng   +14 more
wiley   +1 more source

Sex Specific Transcriptional Regulation of Gonadal Steroidogenesis in Teleost Fishes

Frontiers in Endocrinology, 2022
Partigya Sharma, Shriya Purohit, Sachin Kothiyal, Shilpa Negi, Indrashis Bhattacharya   +4 more
doaj   +1 more source

17β-Estradiol Effects in Skeletal Muscle: A ³¹P MR Spectroscopic Imaging (MRSI) Study of Young Females during Early Follicular (EF) and Peri-Ovulation (PO) Phases

Diagnostics
The natural variation in estrogen secretion throughout the female menstrual cycle impacts various organs, including estrogen receptor (ER)-expressed skeletal muscle.
Jimin Ren, Luis Rodriguez, Talon Johnson, Anke Henning, Yasin Y. Dhaher   +4 more
doaj   +1 more source

Estrogen Receptor Beta in Cancer: an Attractive Target for Therapy

, 2012
While it is well documented that the mitogenic actions of estrogens are critical in the development and progression of human breast and some gynecologic cancers, only latest data demonstrate a crucial involvement of estrogen-signaling in the ...
Scambia, Giovanni, Ferrandina, Maria Gabriella, Gallo, Daniela, De Stefano, Ilaria   +3 more
core   +1 more source