Results 161 to 170 of about 430,922 (218)
Some of the next articles are maybe not open access.
The Role of Estrogen and Estrogen Receptors in Chemoresistance
Current Medicinal Chemistry, 2011Drug resistance is one of the major obstacles limiting the success of cancer chemotherapy. Biological mechanisms contributing to drug resistance may be present de novo and related to inherent features or may be raised after exposure to anticancer drugs. In recent years, both clinical observations and experimental studies suggested that steroid hormones
M, Sui, H, Zhang, W, Fan
openaire +2 more sources
Enzymatic treatment of estrogens and estrogen glucuronide
Journal of Environmental Sciences, 2009Natural and synthetic estrogens from sewage treatment systems are suspected to influence the reproductive health of the animals in the rivers. In this article, we investigated the enzymatic treatment of three estrogens (estrone, 17beta-estradiol, and 17alpha-ethynyletstradiol) by a fungal laccase which oxidize phenolic compounds with dissolved oxygen ...
Takaaki, Tanaka +6 more
openaire +2 more sources
Biological Role of Estrogen and Estrogen Receptors
Critical Reviews in Biochemistry and Molecular Biology, 2002(2002). Biological Role of Estrogen and Estrogen Receptors. Critical Reviews in Biochemistry and Molecular Biology: Vol. 37, No. 1, pp. 1-28.
Stefan, Nilsson, Jan-Ake, Gustafsson
openaire +2 more sources
Estrogen and estrogen receptors in thyroid carcinomas
Journal of Surgical Oncology, 1991AbstractThyroid tissues, composed of normal thyroid (10 cases), Graves' thyroid (4), and papillary carcinoma (10), were measured for the presence of receptors for estrogen (ER) using an enzyme‐immunoassay method. The mean value of ER in papillary carcinoma tissues (4.0 ± 3.6 fmol/mg protein) was higher than that in normal thyroid tissues (0.8 ± 0.4 ...
Y, Mizukami +5 more
openaire +2 more sources
Estrogen and estrogen receptors of breast cancer
Journal of Surgical Oncology, 1975AbstractHuman breast cancer can be divided into a group that contains specific receptor sites for estrogen and a group without such specific estrogen‐binding sites. The presence of specific estrogen receptors in some tumors indicating hormonal dependency has been shown to be of predictive value for endocrine treatment.
V, Sahadevan +3 more
openaire +2 more sources
International Journal of Gynecology & Obstetrics, 1990
The main types of pharmacologic therapy used to treat the hormone deficiency of menopause are parenteral and oral administrations of estrogen. Parenteral administration results in predictable absorption without major intermediary metabolism, whereas all oral estrogens are subject to intestinal metabolism before entering the systemic circulation ...
openaire +2 more sources
The main types of pharmacologic therapy used to treat the hormone deficiency of menopause are parenteral and oral administrations of estrogen. Parenteral administration results in predictable absorption without major intermediary metabolism, whereas all oral estrogens are subject to intestinal metabolism before entering the systemic circulation ...
openaire +2 more sources
Estrogen or estrogen receptor?
Trends in Endocrinology & Metabolism, 2003View Large Image | Download PowerPoint SlideAs a clinical breast oncologist, I was eager to review Endocrine Therapy in Breast Cancer. Hormonal manipulation has been the predominant form of breast cancer treatment for >50 years. Surgical ablation, high-dose estrogens, LHRH agonists and antiestrogens have all shown clinical benefit.
openaire +1 more source
Estrogen Receptors and Anti-Estrogen Therapies
2006The realisation that breast cancer growth is regulated by the hormone estrogen led to the development of tamoxifen as the first target-directed cancer drug. Clearly, there is considerable headway to be made in further elucidating estrogen receptor function, in particular in identifying the mechanisms underlying endocrine resistance.
Lakjaya, Buluwela +3 more
openaire +2 more sources
Estrogen and neuroinflammation
Urology, 2001Women have a higher incidence of inflammatory disorders than men and also appear to perceive painful stimuli differently. It has been suggested that neuroinflammation plays a role in painful bladder disorders of uncertain etiology, such as interstitial cystitis.
D E, Bjorling, Z Y, Wang
openaire +2 more sources
1978
Publisher Summary This chapter discusses the estrogens in pregnancy. A notable characteristic of normal human pregnancy is the extensive production of a variety of biologically active substances. These include (1) the protein hormones human chorionic gonadotropin and human placental lactogen, (2) the enzymes heat-stable alkaline phosphatase and ...
M, Levitz, B K, Young
openaire +2 more sources
Publisher Summary This chapter discusses the estrogens in pregnancy. A notable characteristic of normal human pregnancy is the extensive production of a variety of biologically active substances. These include (1) the protein hormones human chorionic gonadotropin and human placental lactogen, (2) the enzymes heat-stable alkaline phosphatase and ...
M, Levitz, B K, Young
openaire +2 more sources