Results 81 to 90 of about 996,617 (405)

Risk of Venous Thromboembolism in Transgender People Undergoing Hormone Feminizing Therapy: A Prevalence Meta-Analysis and Meta-Regression Study

Frontiers in Endocrinology, 2021
BackgroundAlthough venous thromboembolism (VTE) is a recognized side effect of some formulations of estrogen therapy, its impact in transgender people remains uncertain. The aim of this study was to define pooled prevalence estimate and correlates of VTE
Maria Totaro, Sara Palazzi, Chiara Castellini, Antonio Parisi, Federica D’Amato, Daniele Tienforti, Marco Giorgio Baroni, Marco Giorgio Baroni, Sandro Francavilla, Arcangelo Barbonetti   +9 more
doaj   +1 more source

Effect of cyclosporine on hepatic cytosolic estrogen and androgen receptor levels before and after partial hepatectomy [PDF]

, 1990
Estrogen and androgen receptors within the liver have been reported to modulate the hepatic regenerative response to partial hepatectomy. Moreover, cyclosporine has several untoward effects that might occur as a consequence of alterations in sex hormone ...
A Francavilla, A Francavilla, A. Francavilla, AK Roy, AM Hoyumpa, B Fisher, BA Stoll, CW Bardin, D Kahn, D. H. Van Thiel, D. Kahn, DH Thiel Van, F Kern Jr, G Klatskin, GC Chamness, GM Higgins, H. Lai, I Kam, J. S. Gavaler, JA Gustafsson, JA McGowan, JK Baum, L. Makowka, LE Porter, LJ Bennion, M Salizzori, OH Lowry, P. K. Eagon, PK Eagon, PK Eagon, RY Calne, SB Cardon, T. E. Starzl, TE Starzl   +33 more
core   +1 more source

Reduction in Renal Relapse and Preservation of Long‐Term Kidney Function After Lupus Low Disease Activity in Patients With Lupus Nephritis

Arthritis Care &Research, EarlyView.
Objective Lupus low disease activity state (LLDAS) is a validated treatment target in systemic lupus erythematosus (SLE), but limited studies have explored the role of LLDAS in lupus nephritis (LN). This study aims to investigate the frequency and predictors of LLDAS attainment and its benefit on LN relapse and renal function preservation in patients ...
Chak Kwan Cheung, Desmond Y. H. Yap, Ka Lai Lee, Philip H. Li, Iris Y. K. Tang, Chak Sing Lau, Shirley C. W. Chan   +6 more
wiley   +1 more source

Prevalence, determinants and outcomes of low disease activity and remission attainment in SLE patients with clinically active disease

Arthritis Care &Research, Accepted Article.
Objectives This study aimed to identify the frequency and determinants of Lupus Low Disease Activity State (LLDAS) and Definition of Remission in SLE (DORIS‐remission) attainment in systemic lupus erythematosus (SLE) patients with clinically active disease, and the frequency and determinants of flare and damage accrual after target attainment.
Yanjie Hao, Dylan Hansen, Rangi Kandane‐Rathnayake, Worawit Louthrenoo, Yi‐Hsing Chen, Jiacai Cho, Aisha Lateef, Laniyati Hamijoyo, Shue Fen Luo, Yeong‐Jian Jan Wu, Sandra Navarra, Leonid Zamora, Zhanguo Li, Sargunan Sockalingam, Yasuhiro Katsumata, Masayoshi Harigai, Zhuoli Zhang, Madelynn Chan, Jun Kikuchi, Tsutomu Takeuchi, Sang‐Cheol Bae, Fiona Goldblatt, Sean O'Neill, Kristine (Pek Ling) Ng, Annie Law, BMDB Basnayake, Nicola Tugnet, Sunil Kumar, Cherica Tee, Michael Tee, Naoaki Ohkubo, Yoshiya Tanaka, Shirley Chan, CS Lau, Vera Golder, Alberta Hoi, Shereen Oon, Eric Morand, Mandana Nikpour, for the Asia Pacific Lupus Collaboration   +39 more
wiley   +1 more source

Musculoskeletal and body composition response to high-dose testosterone with finasteride after chronic incomplete spinal cord injury—a randomized, double-blind, and placebo-controlled pilot study

Frontiers in Neurology
BackgroundHigh-dose testosterone replacement therapy (TRT), paired with finasteride (type II 5α-reductase inhibitor), improves body composition, muscle strength, and bone mineral density (BMD) in older men, without inducing prostate enlargement—a side ...
Dana M. Otzel, Dana M. Otzel, Larissa Nichols, Christine F. Conover, Stephen A. Marangi, Jayachandra R. Kura, Dominic K. Iannaccone, David J. Clark, David J. Clark, Chris M. Gregory, Christopher F. Sonntag, Anita Wokhlu, Anita Wokhlu, Hans K. Ghayee, Michael J. McPhaul, Charles E. Levy, Charles A. Plumlee, Charles A. Plumlee, Robert B. Sammel, Robert B. Sammel, Kevin T. White, Joshua F. Yarrow, Joshua F. Yarrow, Joshua F. Yarrow, Joshua F. Yarrow   +24 more
doaj   +1 more source

The Immune System Is a Natural Target for Estrogen Action: Opposing Effects of Estrogen in Two Prototypical Autoimmune Diseases

Frontiers in Immunology, 2016
Analogous to other physiological systems, the immune system also demonstrates remarkable sex differences. Although the reasons for sex differences in immune responses are not precisely understood, it potentially involves differences in sex hormones ...
H. Waldmann, S. Ahmed, D. Khan
semanticscholar   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients with Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, Accepted Article.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; NCT04179032) used three‐weight‐band ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) network investigators   +14 more
wiley   +1 more source

Letrozole Administration as a New Way of Regulating Reproductive Activity in Female Quail

Journal of Applied Poultry Research, 2019
SUMMARY: We investigated the effects of letrozole as a contraceptive on egg production and serum sex hormones in laying quails. Several female reproductive disorders are the most common causes that require stopping egg production in laying and breeding ...
Nesar Zandi, Amjad Farzinpour, Asaad Vaziry   +2 more
doaj   +1 more source

All Sites but Skin Cancer Incidences Analyzed Worldwide by Sex, Age, and Skin Type Over Time (1955-2007), Advancing Age, and UVB Dose Reveals Important Carcinogenic Drivers [PDF]

, 2017
Because we observed increasing incidences over time, advancing age, higher estrogen levels, decreasing UVB (290-315 nm) doses, or lower vitamin D3, and Human Papillomavirus hiding in immune-privileged sites of hair follicles play roles in melanoma, we ...
Godar, Dianne E., Gurov, Rossen, Merrill, Stephen   +2 more
core   +1 more source

Placental weight and mortality in premenopausal breast cancer by tumor characteristics [PDF]

, 2013
Placental weight may be regarded as an indirect marker of hormone exposures during pregnancy. There is epidemiological evidence that breast cancer mortality in premenopausal women increases with placental weight in the most recent pregnancy.
Adolfsson, J., Bahmanyar, S., Cnattingius, S., Fornander, T., Hajiebrahimi, M.H., Lambe, M., Wärnberg, F.   +6 more
core   +1 more source