Results 301 to 310 of about 2,836,003 (403)

Rotenoids from the Roots of Vicia faba L. (Fabaceae): Structural Characterization, Cytotoxic Effects, and Molecular Docking

Chemistry &Biodiversity, EarlyView.
ABSTRACT The chemical study of the ethanolic extract from the roots of Vicia faba led to the isolation of two isoflavonoids, alfalone and 8‐O‐methylretusine, as well as a mixture of rotenoids, including clitoriacetal and clitoriacetal B, the latter of which is reported for the first time.
Victor Menezes Sipoloni, João Victor Silva‐Silva, Elthon G. Ferreira, Eric Yoshitaka Lee, João Marcos Batista Junior, Miriam Uemi, Lívia Soman de Medeiros, Paula C. Jimenez, Thiago A. M. Veiga   +8 more
wiley   +1 more source

Estradiol, via estrogen receptor β signaling, mediates stress-susceptibility in the male brain. [PDF]

Mol Psychiatry
Georgiou P, Postle AF, Mou TM, Potter LE, An X, Zanos P, Patton MS, Pultorak KJ, Clark SM, Ngyuyen V, Powels CF, Prokai-Tatrai K, Kirmizis A, Merchenthaler I, Prokai L, McCarthy MM, Mathur BN, Gould TD.   +17 more
europepmc   +1 more source

A phase Ib/II trial of atezolizumab with cobimetinib or idasanutlin in metastatic estrogen receptor positive breast cancer. [PDF]

NPJ Breast Cancer
Mezzanotte-Sharpe J, Taylor BC, Gonzalez-Ericsson PI, Sanchez V, Ocampo AA, Marshall JL, Steele JA, Sanders ME, Mayer IA, Balko JM, Kennedy LC.   +10 more
europepmc   +1 more source

Interaction between zearalenone, an estrogenic mycotoxin, and the estrogen receptor of the rat brain

, 1982
Motoji Kitagawa, Fumio Tashiro, Yuji Ueno   +2 more
openalex   +2 more sources

Functionalized in Triplicate: A Ring‐By‐Ring Approach to Tailored Prodiginine Derivatives for Site‐Specific Conjugation Through Click Chemistry

Chemistry – A European Journal, EarlyView.
Prodigiosin is a potent cytotoxic alkaloid but lacks target selectivity. We advance functionalization of all three pyrrole rings of prodigiosin to enable site‐specific conjugation via click chemistry. The presented azide‐ and maleimide‐functionalized prodiginines are suitable for generating covalent prodiginine conjugates and attaching auspicious ...
T. Moritz Weber, Jörg Pietruszka
wiley   +1 more source

Predicting estrogen receptor status from HE-stained breast cancer slides using artificial intelligence. [PDF]

Front Med (Lausanne)
Høibø M, Spiske U, Pedersen A, Ytterhus B, Akslen LA, Wik E, Askeland C, Reinertsen I, Smistad E, Valla M.   +9 more
europepmc   +1 more source

Deciphering the transcriptomic landscape of early HR+/HER2− breast cancer in very young women

Cancer Communications, EarlyView.
Iris Garrido‐Cano, Marta Tapia, Juan Carbonell, Carlos Peña, Sandra Torres‐Ruiz, Anna Ágreda‐Roca, Ana Lameirinhas, Cristina Tebar, Octavio Burgués, Cristina Hernando, Ana Lluch, Fara Brasó‐Maristany, Aleix Prat, Begoña Bermejo, María Teresa Martínez, Juan Miguel Cejalvo   +15 more
wiley   +1 more source

Development of Carborane‐Based Halogenated Naphthyridinone‐Analogues as Cannabinoid Receptor Type 2 (CB2R) Ligands

ChemMedChem, EarlyView.
There is no suitable radioligand for positron emission tomography imaging of CB2R overexpression for routine clinical usage. Herein, the synthesis, characterization, binding affinity, and docking studies of carborane‐based halo‐substituted naphthyridinone derivatives as CB2R ligands are presented.
Lea Ueberham, Winnie Deuther‐Conrad, Peter Lönnecke, Aleksandr Kazimir, Evamarie Hey‐Hawkins   +4 more
wiley   +1 more source

LNS8801: An Enantiomerically Pure Agonist of the G Protein-Coupled Estrogen Receptor Suitable for Clinical Development. [PDF]

Cancer Res Commun
Natale CA, Mercado S, Zhuang R, Aguirre-Portolés C, Olayide I, Arnatt CK, Seykora JT, Garyantes TK, Luke W, Ridky TW.   +9 more
europepmc   +1 more source

Inhibition of uterine estrogen receptor transformation by sodium molybdate.

, 1980
G. Shyamala, Linda S. Leonard
openalex   +1 more source