Results 161 to 170 of about 784,665 (196)
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Critical Reviews™ in Eukaryotic Gene Expression, 2002
Today we have to consider the existence of two estrogen receptors, alpha and beta, in our attempts to understand the role of estrogen receptors in physiology and pathology, and to explain the pharmacology of estrogens, antiestrogens, and SERMs. Both ERalpha and ERbeta belong to the large family of nuclear receptors that function as hormone-dependent ...
Stefan, Nilsson, Jan-Ake, Gustafsson
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Today we have to consider the existence of two estrogen receptors, alpha and beta, in our attempts to understand the role of estrogen receptors in physiology and pathology, and to explain the pharmacology of estrogens, antiestrogens, and SERMs. Both ERalpha and ERbeta belong to the large family of nuclear receptors that function as hormone-dependent ...
Stefan, Nilsson, Jan-Ake, Gustafsson
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The histochemistry of estrogen receptors
Histochemistry, 1981Estrogen receptors in frozen section of the rat uterus were demonstrated by a radiolabeled ligand binding technique. The bound hormone was extracted with ethanol and measured by liquid scintillation. The binding of 3H-estradiol-17 beta at various molar concentrations was inhibited by a 100-fold excess of DES, and the bound 3H-estradiol resisted ...
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Journal of Mammary Gland Biology and Neoplasia, 1998
Estrogen receptor (ER)3 gene expression in breast epithelium is an intricately regulated event. The human ER gene is transcribed from at least three different promoters which are expressed in a cell- and tissue-specific manner, and result in mRNA isoforms with unique 5'-untranslated exons.
T A, Hopp, S A, Fuqua
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Estrogen receptor (ER)3 gene expression in breast epithelium is an intricately regulated event. The human ER gene is transcribed from at least three different promoters which are expressed in a cell- and tissue-specific manner, and result in mRNA isoforms with unique 5'-untranslated exons.
T A, Hopp, S A, Fuqua
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An update on estrogen receptors
Seminars in Perinatology, 2000The discovery of a second estrogen receptor (ER), ERbeta, has led to a complete change in our views on estrogen action. The previous dogmatic view that ERalpha represented the only estrogen receptor led to a static and simplistic concept of mechanisms of estrogen action with conceptual limitations in the development of novel estrogenic and ...
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The standardization of estrogen receptors
The Journal of Steroid Biochemistry and Molecular Biology, 1993Tumour estrogen receptor (ER) status may determine the medical treatment of a patient with breast cancer; yet inter-laboratory results can vary markedly, particularly when absolute cut-offs in fmol/mg cytosol protein are used. The use of standardized log units is proposed to permit greater inter-laboratory comparability.
Judy-Anne W. Chapman +11 more
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JAMA: The Journal of the American Medical Association, 1977
To the Editor.— Kiang and Kennedy (238:59-60, 1977) have presented an interesting idea that may prove to be useful in the differential diagnosis of adenocarcinomas of unknown primary site. Unfortunately, however, the evidence offered hardly appears to justify their claim that positive estrogen receptor assays can indicate that metastases arose from ...
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To the Editor.— Kiang and Kennedy (238:59-60, 1977) have presented an interesting idea that may prove to be useful in the differential diagnosis of adenocarcinomas of unknown primary site. Unfortunately, however, the evidence offered hardly appears to justify their claim that positive estrogen receptor assays can indicate that metastases arose from ...
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JAMA: The Journal of the American Medical Association, 1977
L E, Posey +8 more
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L E, Posey +8 more
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The Role of Estrogen Receptors and Their Signaling across Psychiatric Disorders
International Journal of Molecular Sciences, 2021Tae Young Lee +2 more
exaly